Anti-HCN2 Antibody FL490 Conjugate (N71/37)

Name: Anti-HCN2 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-111-FL490
Price: 515.0 USD
Availability: InStock

Our Anti-HCN2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N71/37. It detects mouse and rat HCN2, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

SKU: 75-111-FL490

Volume: 200 µL

Variant

Price:

$515.00

Quantity:

Product Details

Target

HCN2

Target Description

HCN2 is a member of the hyperpolarization-activated cyclic nucleotide gated channel family, also known as pacemaker channels. This family has a role in rhythmic activity of the heart and firing neurons. HCN channels are made up of four subunits, HCN1-4 and can be formed in multiple combinations. HCN2 is expressed throughout the brain and in high levels in thalamic and brainstem nuclei.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N71/37

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Hcn2

Molecular Weight

95 kDa

Antigen

Fusion protein amino acids 761-863 (cytoplasmic C-terminus) of rat HCN2 (accession number Q9JKA9) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939416

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity against HCN1

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2

UniProt Details

UniProt (Human): Q9UL51
UniProt (Immunogen Species): Q9JKA9

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Anti-HCN2 Antibody FL490 Conjugate (N71/37)

SKU: 75-111-FL490

Product Details

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