Anti-HCN2 Antibody (N71/37)

Our Anti-HCN2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N71/37. It detects mouse and rat HCN2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.



SKU: 75-111

Volume: 100 µL
1-2 business days
Price:
Sale price$374.00

Product Specific References for Applications and Species

Immunocytochemistry: Mouse
PMID Dilution Publication
344293571:100Schlusche, A.K., et al. 2021. Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice. PNAS: USA, e2009393118.
Immunocytochemistry: Rat
PMID Dilution Publication
235163511:200Abbas, S.Y., et al. 2013. Directional summation in non-direction selective retinal ganglion cells.. PLOS Computational Biology, e1002969.
Immunohistochemistry: Mouse
PMID Dilution Publication
28213444not listedSrinivas, K.V., et al. 2017. The Dendrites of CA2 and CA1 Pyramidal Neurons Differentially Regulate Information Flow in the Cortico-Hippocampal Circuit. Journal of Neuroscience, 3276-3293.
218809181:400Felix, R.A., et al. 2011. Sound rhythms are encoded by postinhibitory rebound spiking in the superior paraolivary nucleus.. Journal of Neuroscience, 12566-12578.
Immunohistochemistry: Rat
PMID Dilution Publication
363956911:500Choi, K., et al. 2022. Presynaptic HCN Channel Activity Is Required For The Expression Of Long-Term Potentiation At Lateral Amygdala To Basal Amygdala Synapses. Biochemical And Biophysical Research Communications, 100-107.
22832570not listedAlmanza, A., et al. 2012. Molecular identity, ontogeny, and cAMP modulation of the hyperpolarization-activated current in vestibular ganglion neurons.. Journal of Neurophysiology, 2264-2275.
219455371:300Kanyshkova, T., et al. 2012. Differential regulation of HCN channel isoform expression in thalamic neurons of epileptic and non-epileptic rat strains.. Neurobiology of Disease, 450-461.
219384021:1000Anderson, W.D., et al. 2011. Properties and functional implications of I (h) in hippocampal area CA3 interneurons.. Pflügers Archiv, 895-912.
211599671:2000Giesbrecht, C.J., et al. 2010. Countervailing modulation of Ih by neuropeptide Y and corticotrophin-releasing factor in basolateral amygdala as a possible mechanism for their effects on stress-related behaviors.. Journal of Neuroscience, 16970-16982.
202200801:25Yi, E., et al. 2010. Dendritic HCN channels shape excitatory postsynaptic potentials at the inner hair cell afferent synapse in the mammalian cochlea.. Journal of Neurophysiology, 2532-2543.
18668683not listedBuniel, M., et al. 2008. Distribution of voltage-gated potassium and hyperpolarization-activated channels in sensory afferent fibers in the rat carotid body.. Journal of Comparative Neurology, 367-377.
Western Blot: Human
PMID Dilution Publication
26644354not listedGong, B., et al. 2016. Developing high-quality mouse monoclonal antibodies for neuroscience research–approaches, perspectives and opportunities. New Biotechnology, 551-564.
Western Blot: Mouse
PMID Dilution Publication
344293571:500Schlusche, A.K., et al. 2021. Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice. PNAS: USA, e2009393118.
336753591:1000Yu, D., et al. 2021. The Transcription Factor Shox2 Shapes Neuron Firing Properties and Suppresses Seizures by Regulation of Key Ion Channels in Thalamocortical Neurons.. Cerebral Cortex, 3194-3212.
270473381:500Fan, J., et al. 2016. Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP−/− Mice. Frontiers of Cellular Neuroscience, 74.
26644354not listedGong, B., et al. 2016. Developing high-quality mouse monoclonal antibodies for neuroscience research–approaches, perspectives and opportunities. New Biotechnology, 551-564.
23821600not listedStoenica, L., et al. 2013. HCN1 subunits contribute to the kinetics of I(h) in neonatal cortical plate neurons.. Developmental Neurobiology, 785-797.
22880098not listedYing, S.W., et al. 2012. Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.. PLoS One, e4756.
19574228not listedYe, B., et al. 2009. Proteolytic processing of HCN2 and co-assembly with HCN4 in the generation of cardiac pacemaker channels.. The Journal of Biological Chemistry, 25553-25559.
Western Blot: Rat
PMID Dilution Publication
35377277not listedSalinas-Luypaert, C., et al. 2022. Gene knockdown of HCN2 ion channels in the ventral tegmental area reduces ethanol consumption in alcohol preferring rats. American Journal of Drug and Alcohol Abuse, 165-175.
235367711:1000Brewster, A.L., et al. 2013. Rapamycin reverses status epilepticus-induced memory deficits and dendritic damage.. PLoS One, e57808.
219050791:1500McClelland, S., et al. 2011. Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy.. Annals of Neurology, 454-464.
Additional Publications: Unspecified
PMID Publication
24460767Rivera-Meza, M., et al. 2014. Overexpression of hyperpolarization-activated cyclic nucleotide-gated channels into the ventral tegmental area increases the rewarding effects of ethanol in UChB drinking rats.. Alcoholism: Clinical and Experimental Research, 911-920.
19336273Peters, C.J., et al. 2009. In situ co-distribution and functional interactions of SAP97 with sinoatrial isoforms of HCN channels.. Journal of Molecular and Cellular Cardiology, 636-643.

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