Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with untagged GRK5, GRK6 and Kv2.1 plasmids and probed with N142/28 TC supe.
Anti-GRK6A/B Antibody
SKU: 75-176
Bulk Order Anti-GRK6A/B Antibody
Product Details
GRK6A/B
G-protein coupled receptor kinase 6 is encoded by the gene GRK6. GRK6 is a member of the protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily. GRK6 phosphorylates the activated forms of G-protein coupled receptors, thus initiating their deactivation. GRK6 is expressed in the brain in striatal neurons and spleen. No disorders were found to be associated with GRK6.
Purified
1 mg/mL
Monoclonal
N142/28
IgG1
ICC, WB
Mouse
Grk6 Gprk6
65 kDa
Fusion protein amino acids 371-576 (C-terminus) of mouse GRK6A(also known as G protein-coupled receptor kinase 6A and Gprk6A, accession number O70293); Rat: 98% identity (203/206 amino acids identical); Human: 95% identity (197/206 amino acids identical); 100% identity with GRK6B (189/189 amino acids identical, amino acids 371-559); Greater than 55% identity with GRK5 and GRK4
Mouse
AB_2115469
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.