Anti-GRK6A/B Antibody (N142/28)

Name: Anti-GRK6A/B Antibody
Brand: NeuroMab
SKU: 75-176
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Available Conjugates

490

550

594

650

Product Type

Primary Antibody

Species Reactivity

Mouse

Clone

N142/28

Applications

ICC, WB

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Grk6 Gprk6

Molecular Weight

65 kDa

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Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with untagged GRK5, GRK6 and Kv2.1 plasmids and probed with N142/28 TC supe.

Volume: 100 µL

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Price:

$308

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Product Details

Target

GRK6A/B

Target Description

G-protein coupled receptor kinase 6 is encoded by the gene GRK6. GRK6 is a member of the protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily. GRK6 phosphorylates the activated forms of G-protein coupled receptors, thus initiating their deactivation. GRK6 is expressed in the brain in striatal neurons and spleen. No disorders were found to be associated with GRK6.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N142/28

Isotype

IgG1

Applications

ICC, WB

Host Species

Mouse

Gene Name

Grk6 Gprk6

Molecular Weight

65 kDa

Antigen

Fusion protein amino acids 371-576 (C-terminus) of mouse GRK6A (accession number O70293) produced recombinantly in E. Coli

Species Reactivity

Mouse

Antibody Registry ID

AB_2115469

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.104

Conjugate

Unconjugated

Specificity

Cross-reacts with GRK6B

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6)

UniProt Details

UniProt (Human): P43250
UniProt (Immunogen Species): O70293

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Anti-GRK6A/B Antibody (N142/28)

Available Conjugates

Anti-GRK6A/B Antibody
SKU: 75-176

Bulk Order Anti-GRK6A/B Antibody

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Anti-GRK6A/B Antibody (N142/28)

Available Conjugates

Anti-GRK6A/B Antibody SKU: 75-176

Bulk Order Anti-GRK6A/B Antibody

Product Details

Anti-GRK6A/B Antibody
SKU: 75-176