Anti-GluN1/NR1 Glutamate Receptor Antibody FL650 Conjugate (N308/48)

Name: Anti-GluN1/NR1 Glutamate Receptor Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-272-FL650
Price: 515.0 USD
Availability: InStock

Our Anti-GluN1/NR1 glutamate receptor mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N308/48. It detects human, mouse, and rat GluN1/NR1 glutamate receptor, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

490

550

594

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Data Sheet

SKU: 75-272-FL650

Volume: 200 µL

Variant

Price:

$515.00

Quantity:

Product Details

Target

GluN1/NR1 glutamate receptor

Target Description

Glutamate receptor 1, NMDA 1, or GluN1/NR1 also known as subunit 1 of the N-methyl-D-aspartate (NMDA) receptor. It is a member of the glutamate receptor channel superfamily and is a heteromeric glutamate-gated calcium ion channel. GluN1 is essential for synaptic function in the brain. GluN1 is expressed throughout the brain in cerebellum, thalamus, olfactory bulb and cortex in the membrane at postsynaptic density. GluN1 plays a key role in synaptogenesis, synaptic plasticity, memory acquisition and learning. Mutations in the GluN1 gene are associated with intellectual disability and cortical visual impairment and movement disorders.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N308/48

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Grin1 Nmdar1

Molecular Weight

105 kDa

Antigen

Fusion protein amino acids 42-361 (extracellular N-terminus) of rat NR1 (accession number P35439) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939979

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)

UniProt Details

UniProt (Human): Q05586
UniProt (Immunogen Species): P35439-2

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Anti-GluN1/NR1 Glutamate Receptor Antibody FL650 Conjugate (N308/48)

SKU: 75-272-FL650

Product Details

Bulk Order Anti-GluN1/NR1 Glutamate Receptor Antibody FL650 Conjugate

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