Fibronectin Leucine Rich Transmembrane Protein 3 is encoded by the gene FLRT3. FLRT3 is a member of the fibronectin leucine rich transmembrane (FLRT) family. FLRT3 functions in cell-cell adhesion, cell migration, and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. FLRT3 is expressed in adult brain, embryonic rostral thalamus neurons, and the neonate eye. Diseases associated with FLRT3 included Hypogonadotropic Hypogonadism 21 With or Without Anosmia, Kallmann Syndrome, and Hypogonadotropic Hypogonadism 7 With or Without Anosmia.
Purified by Protein A chromatography
Fusion protein amino acids 29-526 (extracellular domain) of mouse Flrt3 (accession number Q8BGT1) produced recombinantly in E. Coli
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL490 Ex: 491 nm, Em: 515 nm
No cross-reactivity against Flrt1 or Flrt2
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
12 months from date of receipt
Shipped on ice packs
Leucine-rich repeat transmembrane protein FLRT3 (Fibronectin leucine rich transmembrane protein 3)