Transfected cell immunofluorescence: COS cells expressing Myc-tagged Flrt3. Red = Myc, Green = N353/13, Blue = Hoechst nuclear stain.
Bulk Order Anti-Flrt3 Antibody
Leucine-rich repeat transmembrane protein FLRT3 (Fibronectin leucine rich transmembrane protein 3)
Fibronectin Leucine Rich Transmembrane Protein 3 is encoded by the gene FLRT3. FLRT3 is a member of the fibronectin leucine rich transmembrane (FLRT) family. FLRT3 functions in cell-cell adhesion, cell migration, and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. FLRT3 is expressed in adult brain, embryonic rostral thalamus neurons, and the neonate eye. Diseases associated with FLRT3 included Hypogonadotropic Hypogonadism 21 With or Without Anosmia, Kallmann Syndrome, and Hypogonadotropic Hypogonadism 7 With or Without Anosmia.
Fusion protein amino acids 29-526 (extracellular domain) of mouse Flrt3 (also known as Leucinerich repeat transmembrane protein FLRT3, Fibronectin-like domain-containing leucine-rich transmembrane protein 3, KIAA1469 and UNQ856/PRO1865, accession number Q8BGT1); Rat: 99% identity (496/498 amino acids identical); Human: 96% identity (480/498 amino acids identical); 50% identity with Flrt1 and Flrt2
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