Anti-Epithelial Cell Adhesion Molecule (Ep-CAM) Antibody FL594 Conjugate (ESA 214)
Our Anti-Epithelial Cell Adhesion Molecule mouse monoclonal primary antibody from Antibodies Incorporated is produced in-house from hybridoma clone ESA 214. It detects human Epithelial Cell Adhesion Molecule, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
SKU: MM-1014-FL594
Product Details
Epithelial Cell Adhesion Molecule
Epithelial specific antigen is a transmembrane glycoprotein (40 kDa) also known as ESA or epithelial cellular adhesion molecule (Ep-CAM). This protein is expressed on basolateral cell surface in most simple epithelia and vast majority of cancers. According to the “Cancer Stem Cells” (CSC) theory, tumors are not viewed as simple monoclonal expression of transformed cells, but rather as complex tissue where abnormal growth is driven by a minority pathological CSC pool that on one hand has acquired tumor related features such as uncontrolled growth and ability to form metasis and on the other hand maintains its inherent capacity to self renew and differentiate into a phenotypic ally heterogeneous, although aberrant progency. This antibody has been used recently to characterize the EpCAM high CD44+ versus EpCAM low/Cd44- indifferent cancer cells.
Purified by Protein A Chromatography
0.5 mg/mL
Monoclonal
ESA 214
IgG1
ICC, IHC
Mouse
EPCAM
40 kDa
Small cell lung carcinoma
Human
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL594 Ex: 594 nm, Em: 615 nm
No cross-reactivity reported
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used in Western blot.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
12 months from date of receipt
Shipped on ice packs
Ep-CAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1
UniProt (Human): P16422
UniProt (Immunogen Species): P16422
UniProt (Immunogen Species): P16422