Anti-Doc2B Antibody FL650 Conjugate (N150/21)
Our Anti-Doc2b mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N150/21. It detects mouse and rat Doc2b, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
SKU: 75-214-FL650
Product Details
Doc2b
Double C2-like domain-containing protein beta or Doc2b is encoded by the gene DOC2b. Doc2b functions as a calcium sensor which positively regulates soluble NSF attachment receptor (SNARE) dependent fusion of vesicles with membranes. Doc2b binds phospholipids and may act at the priming stage of membrane fusion by modifying membrane curvature to stimulate fusion. Doc2b is expressed in pancreatic cells, endocrine cells and brain, where it is highly expressed in neurons. (Friedrich et al.Neurosci., July 2, 2008 • 28(27):6794 – 6806)
Purified by Protein A chromatography
0.5 mg/mL
Monoclonal
N150/21
IgG1
ICC, IHC
Mouse
Doc2b
45 kDa
Fusion protein amino acids 1-216 (N-terminus) of rat Doc2b (accession number P70610) produced recombinantly in E. Coli
Mouse, Rat
AB_2939795
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL650 Ex: 655 nm, Em: 676 nm
Does not cross-react with Doc2a
Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
12 months from date of receipt
Shipped on ice packs
Double C2-like domain-containing protein beta (Doc2-beta)
UniProt (Human): Q14184
UniProt (Immunogen Species): P70610
UniProt (Immunogen Species): P70610