Anti-Copper ATPase 2 (Wilson's Disease Protein) Antibody FL650 Conjugate (L62/29)

Name: Anti-Copper ATPase 2 (Wilson's Disease Protein) Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-143-FL650
Price: 486.0 USD
Availability: InStock

Our mouse Copper ATPase 2 (Wilson's disease protein) FL650 conjugate monoclonal antibody from NeuroMab is produced in-house from clone L62/29. It detects human, mouse, and rat Copper ATPase 2 (Wilson's disease protein) and is purified by Protein A chromatography. Works in IHC.

Anti-Copper ATPase 2 (Wilson's Disease Protein) Antibody FL650 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

Biotin

Carrier-Free

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Data Sheet

SKU: 75-143-FL650

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Copper ATPase 2 (Wilson's disease protein)

Scientific Background

Copper-transporting ATPase 2 or Copper-transporting ATPase Beta is encoded by the gene ATP7B and belongs to the cation transport ATPase (P-type) family. Copper-transporting ATPase 2 is a transmembrane enzyme that functions to provide copper to copper requiring proteins in the golgi network and is also to remove excess copper across plasma membranes out of the cell Copper-transporting ATPase 2 is expressed in liver and in lower leves in brain, heart, kidney, placenta and lung. In liver, it is involved in removing copper from hepatocytes into the bile for removal. Diseases associated with this gene include Wilson Disease and Menkes Disease.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

L62/29

Isotype

IgG1

Applications

IHC

Host Species

Mouse

Gene Name

ATP7B PWD WC1 WND

Molecular Weight

160 kDa in rat brain membrane preparations

Immunogen

Synthetic peptide amino acids 3-21 (cytoplasmic N- terminus) of human Copper-transporting ATPase 2 (accession number P35670)

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939531

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Copper-transporting ATPase 2 (EC 3.6.3.54) (Copper pump 2) (Wilson disease-associated protein) [Cleaved into: WND/140 kDa]

UniProt ID

P35670

Shipping

Shipped on ice packs

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Anti-Copper ATPase 2 (Wilson's Disease Protein) Antibody FL650 Conjugate (L62/29)

SKU: 75-143-FL650

Product Details

Bulk Order Anti-Copper ATPase 2 (Wilson's Disease Protein) Antibody FL650 Conjugate

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