Chloride Voltage-Gated Channel 4, CLCN4 or H(+)/Cl(-) exchange transporter 4 is encoded by the gene CLCN4 and is a member of the voltage-gated chloride channel (ClC) family. CLCN4 is a proton-coupled chloride transporter. CLCN4 is expressed in skeletal muscle, brain and heart. Diseases associated with this gene include Raynaud-Claes Syndrome and X-Linked Intellectual Disability Syndrome.
Purified by Protein A chromatography
Synthetic peptide amino acids 30-51 (TDRHRKITSKSKESIWEFIKSL, cytoplasmic N-terminus) of rat Clcn4 (accession number P51793)
Human, Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL650 Ex: 655 nm, Em: 676 nm
Does not cross-react with Clcn5
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.