Chloride Voltage-Gated Channel 4, CLCN4 or H(+)/Cl(-) exchange transporter 4 is encoded by the gene CLCN4 and is a member of the voltage-gated chloride channel (ClC) family. CLCN4 is a proton-coupled chloride transporter. CLCN4 is expressed in skeletal muscle, brain and heart. Diseases associated with this gene include Raynaud-Claes Syndrome and X-Linked Intellectual Disability Syndrome.
ICC, IHC, WB
Synthetic peptide amino acids 30-51 (TDRHRKITSKSKESIWEFIKSL, cytoplasmic N-terminus) of rat Clcn4 (also known as H(+)Cl(-) exchange transporter 4, Chloride transporter CIC-4, ChlorideMouse: 100% identity (22/22 amino acids identical); Human: 100% identity (22/22 amino acids identical)
Greater than 60% identity with Clcn5
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Does not cross-react with Clcn5
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.