CUGBP Elav-like family member 4 (CELF4), or Brunol4 is encoded by the gene CELF4. CELF4 is a RNA-binding protein which is involved in the regulation of pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. CELF4 is expressed ubiquitously in tissues, and strongly expressed in brain. Diseases associated with CELF4 include Speech and Communication Disorders and Specific Language Impairment.
Purified by Protein A chromatography
ICC, IHC, WB
Fusion protein amino acids 2-87 (N-terminus) of human Celf4 (accession number Q9BZC1) produced recombinantly in E. Coli
Human, Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Does not cross-react with Celf6
Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from date of receipt
Shipped on ice packs
CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4)