Our Anti-Cavbeta2 Ca2+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N8B/1. It detects human, mouse, and rat Cavbeta2 Ca2+ channel, and is purified by Protein A chromatography. It is great for use in CM, IHC, ICC.
Cavbeta2 Ca2+ channel
Voltage-dependent L-type calcium channel subunit beta-2 or Cav ß2 is encoded by the gene CACNB2. Cavß2 is a cytoplasmic subunit of L type voltage-sensitive calcium channels.These channels facilitate entry of calcium ions into excitable cells are involved in a variety of calcium dependent processes, including neurotransmitter release, muscle contraction, and gene expression. Cav ß2 is expressed heart and brain, and lung. Mutations in this gene are associated with Brugada syndrome.
Purified by Protein A chromatography
Synthetic peptide amino acids 189-205 of rat Cav2 (RSPKPSANSVTSPHSKE; accession number A0A0G2JSZ0)
Human, Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL490 Ex: 491 nm, Em: 515 nm
Does not cross-react with Cavβ1, Cavβ3, Cavβ4
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.