Our Anti-BKbeta2 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N53/32. It detects human, mouse, and rat BKbeta2 K+ channel, and is purified by Protein A chromatography. It is great for use in ICC.
BKbeta2 K+ channel
Calcium-activated potassium channel subunit beta-2, Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 2 or BKbeta2 is encoded by the gene KCNMB2. BKbeta2 can bind to KCNMA1 to form a channel in the calcium activated large conductance (MaxiK channel) family. BKbeta2 acts to modulate the calcium sensitivity and gating kinetics of KCNMA1. BKbeta2 is expressed in the membrane in many tissues including kidney, heart, ovary and brain.
Purified by Protein A chromatography
Fusion protein amino acids 1-41 (N-terminus) and 218-235 (C-terminus) of mouse BKBeta2 (accession number Q9CZM9) produced recombinantly in E. Coli
Human, Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL594 Ex: 594 nm, Em: 615 nm
No cross-reactivity against BKBeta1, BKBeta3 or BKBeta4
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.