Anti-BKbeta2 K+ Channel Antibody (N53/32)

Name: Anti-BKbeta2 K+ Channel Antibody
Brand: NeuroMab
SKU: 75-087
Price: 285.0 USD
Availability: InStock

from NeuroMab Datasheet

filler

Clonality

Monoclonal

Applications

ICC, IP, WB

Host Species

Mouse

Gene Name

Kcnmb2

Molecular Weight

27 kDa

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$Immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] and probed with N53/32 (left) or N52A/42 (right) TC supe.$

Immunoblot against extracts of COS cells transiently transfected with GFP-tagged BKBeta2 or untagged Kv2.1 plasmid and probed with N53/32 (left) or K89/41 (right) TC supe.

Product Details

Target

BKbeta2 K+ channel

Target Description

Calcium-activated potassium channel subunit beta-2, Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 2 or BKbeta2 is encoded by the gene KCNMB2. BKbeta2 can bind to KCNMA1 to form a channel in the calcium activated large conductance (MaxiK channel) family. BKbeta2 acts to modulate the calcium sensitivity and gating kinetics of KCNMA1. BKbeta2 is expressed in the membrane in many tissues including kidney, heart, ovary and brain.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N53/32

Isotype

IgG2a

Applications

ICC, IP, WB

Host Species

Mouse

Gene Name

Kcnmb2

Molecular Weight

27 kDa

Antigen

Fusion protein amino acids 1-41 (N-terminus) and 218-235 (C-terminus) of mouse BKBeta2 (accession number Q9CZM9); Human: 97% (N-terminus) and 100% (C-terminus) identity (40/41 and 18/18 amino acids identical); Mouse: 97% (N-terminus) and 100% (C-terminus) identity (40/41 and 18/18 amino acids identical)

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2131396

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Conjugate

Unconjugated

Specificity

No cross-reactivity against BKBeta1, BKBeta3 or BKBeta4

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Calcium-activated potassium channel subunit beta-2 (BK channel subunit beta-2) (BKbeta2) (Calcium-activated potassium channel, subfamily M subunit beta-2) (Charybdotoxin receptor subunit beta-2) (K(VCA)beta-2) (Maxi K channel subunit beta-2) (Slo-beta-2)

UniProt Details

UniProt (Human): Q9Y691
UniProt (Immunogen Species): Q9CZM9

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Anti-BKbeta2 K+ Channel Antibody (N53/32)

Anti-BKbeta2 K+ Channel Antibody
SKU: 75-087

Product Details

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Anti-BKbeta2 K+ Channel Antibody (N53/32)

Anti-BKbeta2 K+ Channel Antibody SKU: 75-087

Product Details

Anti-BKbeta2 K+ Channel Antibody
SKU: 75-087