Anti-BDNF Antibody (N450/53)

Name: Anti-BDNF Antibody
Brand: NeuroMab
SKU: 75-470
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Available Conjugates

490

550

594

650

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N450/53

Applications

IHC, WB

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Bdnf

Molecular Weight

25-40 kDa

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Immunofluorescence labeling of adult rat hippocampus with N450/53 TC supe (red) and Hoechst nuclear stain (blue)..

Volume: 100 µL

Variant

Price:

$308

Quantity:

Bulk Order Anti-BDNF Antibody

Product Details

Target

BDNF

Target Description

Brain-derived neurotrophic factor is encoded by the gene BDNF and is a member of the neurotrophin family of growth factors. BDNF is a secreted signaling molecule with may important functions including axonal growth, modulation of dendritic growth, the promotion of survival/differentiation of neuronal populations in peripheral and central nervous systems, regulation of synaptic transmission/plasticity and long-term potentiation. BDNF is expressed highly in brain (in the hippocampus, amygdala, cerebral cortex and cerebellum) and expressed in lung, heart and skeletal muscle. Diseases associated with this gene include Congenital Central Hypoventilation Syndrome, Wilms Tumor, Aniridia and Mental Retardation Syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N450/53

Isotype

IgG2b

Applications

IHC, WB

Host Species

Mouse

Gene Name

Bdnf

Molecular Weight

25-40 kDa

Antigen

Fusion protein amino acids 1-249 (full length) of mouse BDNF (accession number P21237) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2722670

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Brain-derived neurotrophic factor (Abrineurin)

UniProt Details

UniProt (Human): P23560
UniProt (Immunogen Species): P21237

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Anti-BDNF Antibody (N450/53)

Available Conjugates

Anti-BDNF Antibody
SKU: 75-470

Bulk Order Anti-BDNF Antibody

Product Details

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Anti-BDNF Antibody (N450/53)

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Anti-BDNF Antibody SKU: 75-470

Bulk Order Anti-BDNF Antibody

Product Details

Anti-BDNF Antibody
SKU: 75-470