Anti-BDNF Antibody (N450/53)

Name: Anti-BDNF Antibody
Brand: NeuroMab
SKU: 75-470
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N450/53

Applications

ICC, IHC, WB

Host Species

Mouse

Format

Purified

Gene Name

Bdnf

Molecular Weight

25-40 kDa

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Immunofluorescence labeling of adult rat hippocampus with N450/53 TC supe (red) and Hoechst nuclear stain (blue)..

Volume: 100 µL

Variant

Price:

$308

Quantity:

Bulk Order Anti-BDNF Antibody

Product Details

Target

Brain-derived neurotrophic factor (Abrineurin)

Target Description

Brain-derived neurotrophic factor is encoded by the gene BDNF and is a member of the neurotrophin family of growth factors. BDNF is a secreted signaling molecule with may important functions including axonal growth, modulation of dendritic growth, the promotion of survival/differentiation of neuronal populations in peripheral and central nervous systems, regulation of synaptic transmission/plasticity and long-term potentiation. BDNF is expressed highly in brain (in the hippocampus, amygdala, cerebral cortex and cerebellum) and expressed in lung, heart and skeletal muscle. Diseases associated with this gene include Congenital Central Hypoventilation Syndrome, Wilms Tumor, Aniridia and Mental Retardation Syndrome.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N450/53

Isotype

IgG2b

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Bdnf

Molecular Weight

25-40 kDa

Antigen

Fusion protein amino acids 1-249 (full length) of mouse BDNF (also known as Brain-derived neurotrophic factor and Abrineurin, accession number P21237)

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2722670

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Brain-derived neurotrophic factor (Abrineurin)

UniProt Details

UniProt (Human): P23560
UniProt (Immunogen Species): P21237

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Anti-BDNF Antibody (N450/53)

Anti-BDNF Antibody
SKU: 75-470

Bulk Order Anti-BDNF Antibody

Product Details

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Anti-BDNF Antibody (N450/53)

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Anti-BDNF Antibody
SKU: 75-470