ADP-ribosylation factor-like protein 6, Bardet-Biedl syndrome 3 protein or BBS3/Arl6 is encoded by the gene ARL6 and is a member of the ARF family withing the small GTPase superfamily. BBS3 acts as a regulator of cellular traffic and has roles in protein transport and membrane trafficking. BBS3 is widely expressed in tissues including brain, eye, heart and kidney. Mutations in this gene are associated with Bardet-Biedl syndrome (BBS).
Purified by Protein A chromatography
ICC, IHC, WB
Fusion protein amino acids 1-186 (full-length) of human ADP-ribosylation factor-like protein 6 (accession number Q9H0F7) produced recombinantly in E. Coli
Human, Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
No cross-reactivity reported
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from date of receipt
Shipped on ice packs
ADP-ribosylation factor-like protein 6 (Bardet-Biedl syndrome 3 protein)