Anti-BAF53a Antibody (N336B/83)

Name: Anti-BAF53a Antibody
Brand: NeuroMab
SKU: 75-330
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

1 Citation

Available Conjugates

490

550

594

650

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N336B/83

Applications

ICC, WB

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

ACTL6A BAF53 BAF53A INO80K

Molecular Weight

53 kDa

Go to Full Product Details

Transfected cell immunoblot: extracts of COS cells transiently transfected with untagged BAF53a, BAF53b or Kv2.1 plasmids and probed with N336B/83 (left) or N52A/42 (right) TC supe. Note that BAF53a is ubiquitously expressed in many different cell types, including COS cells.

Volume: 100 µL

Variant

Price:

$308

Quantity:

Bulk Order Anti-BAF53a Antibody

Product Details

Target

BAF53a

Target Description

Actin-like protein 6A, or BAF Complex 53 KDa Subunit (BAF53a) is encoded by the gene ACTL6A and is a member of actin-related proteins family. It is a subunit of the neuron specific chromatin remodeling complex (nBAF complex). BAF53a is thought to be involved in transcriptional activation and repression of chromatin remodeling. BAF53a is a subunit of the neural progenitors-specific chromatin remodeling complex (npBAF complex). BAF53a is expressed in many different cell types. Diseases associated with ACTL6A include Coffin-siris syndrome and Brachymorphism-Onychodysplasia-Dysphalangism Syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N336B/83

Isotype

IgG2b

Applications

ICC, WB

Host Species

Mouse

Gene Name

ACTL6A BAF53 BAF53A INO80K

Molecular Weight

53 kDa

Antigen

Fusion protein amino acids 43-119 (MVVERDDGSTLMEIDGDKGKQGGPTYYIDTNALRVPRENMEAISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHP, actin subdomain 2) of human BAF53a (accession number O96019) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2315809

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with BAF53b

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Actin-like protein 6A (53 kDa BRG1-associated factor A) (Actin-related protein Baf53a) (ArpNbeta) (BRG1-associated factor 53A) (BAF53A) (INO80 complex subunit K)

UniProt Details

UniProt (Human): O96019
UniProt (Immunogen Species): O96019

Kim S, Kim T, Lee HR, Kong YY, Kaang BK. (2015), 'Mind Bomb-2 Regulates Hippocampus-dependent Memory Formation and Synaptic Plasticity..' Korean J Physiol Pharmacol.. 10.4196/kjpp.2015.19.6.515.

Recover password

Create my account

Anti-BAF53a Antibody (N336B/83)

Available Conjugates

Anti-BAF53a Antibody
SKU: 75-330

Bulk Order Anti-BAF53a Antibody

Product Details

Related Products

Recently Viewed

Anti-BAF53a Antibody (N336B/83)

Available Conjugates

Anti-BAF53a Antibody SKU: 75-330

Bulk Order Anti-BAF53a Antibody

Product Details

Anti-BAF53a Antibody
SKU: 75-330