Anti-Ataxin-1, WT Antibody FL490 Conjugate (N65/37)

Name: Anti-Ataxin-1, WT Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-102-FL490
Price: 460.0 USD
Availability: InStock

Our Anti-Ataxin-1, WT mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N65/37. It detects human, mouse, and rat Ataxin-1, WT, and is purified by Protein A chromatography. It is great for use in ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

SKU: 75-102-FL490

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

Ataxin-1, WT

Target Description

Ataxin1, also known as spinocerebellar ataxia type 1 protein homolog, is a highly conserved DNA-binding protein. Ataxin1 is expressed in brain and can be found at high levels in the cortex and the hypothalamus in neurons. It is also expressed in other tissues. Within the cell, it is highly expressed in the nucleus, and can also be found in the cytoplasm. Mutations in the ataxin-1 gene cause spinocerebellar ataxia type 1.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N65/37

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

Atxn1 Sca1

Molecular Weight

85 kDa

Antigen

Synthetic peptide amino acids 746-761 (RKRRRWSAPETRKLEK) of mouse ataxin-1 (accession number P54254)

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939380

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Minimal cross-reactivity against S751A mutant of Ataxin-1 by ELISA and immunofluorescence and negative by immunoblot (right)

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog)

UniProt Details

UniProt (Human): P54253
UniProt (Immunogen Species): P54254

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Anti-Ataxin-1, WT Antibody FL490 Conjugate (N65/37)

SKU: 75-102-FL490

Product Details

Bulk Order Anti-Ataxin-1, WT Antibody FL490 Conjugate

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