Our Anti-ANO5/TMEM16E mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N421A/85. It detects human ANO5/TMEM16E, and is purified by Protein A chromatography. It is great for use in ICC.
Anoctamin-5, Transmembrane Protein 16E or -ANO5/TMEM16E is encoded by the gene ANO5. ANO5 belongs to the anoctamin family of membrane proteins many of which are calcium-activated chloride channels. ANO5 does not exhibit this channel activity. ANO5 is expressed in brain, heart, kidney, lung, skeletal muscle as well as other tissues. Diseases associated with ANO5 include Gnathodiaphyseal Dysplasia and Miyoshi Muscular Dystrophy 3.
Purified by Protein A chromatography
ANO5 GDD1 TMEM16E
Fusion protein amino acids 1-299 (cytoplasmic N-terminus) of human ANO5 (accession number Q75V66) produced recombinantly in E. Coli
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL650 Ex: 655 nm, Em: 676 nm
Does not cross-react with ANO6/TMEM16F
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
12 months from date of receipt
Shipped on ice packs
Anoctamin-5 (Gnathodiaphyseal dysplasia 1 protein) (Transmembrane protein 16E)