Disintegrin and metalloproteinase domain-containing protein 11 (ADAM 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC)
Disintegrin and metalloproteinase domain-containing protein 11, Metalloproteinase-Like, Disintegrin-Like, Cysteine-Rich Protein, or ADAM11 is encoded by the gene ADAM11 and a member of the ADAM (a disintegrin and metalloproteinase) family. ADAM11 is a single-pass type I membrane protein without catalytic metalloprotease-like properties. It is thought to be a ligand for integrin in the brain. ADAM11 is also weakly detected in the heart, liver and testis.
ICC, IHC, WB
Fusion protein amino acids 243-441 (extracellular domain) of mouse ADAM11 (also known as Disintegrin and metalloproteinase domain-containing protein 11, Metalloproteinase-like disintegrin-like and cysteine-rich protein, MDC and rCG_32562, accession number Q9R1V4); Rat: 100% identity (199/199 amino acids identical); Human: 99% identity (198/199 amino acids identical); 60% identity with ADAM22
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.