Disintegrin and metalloproteinase domain-containing protein 11, Metalloproteinase-Like, Disintegrin-Like, Cysteine-Rich Protein, or ADAM11 is encoded by the gene ADAM11 and a member of the ADAM (a disintegrin and metalloproteinase) family. ADAM11 is a single-pass type I membrane protein without catalytic metalloprotease-like properties. It is thought to be a ligand for integrin in the brain. ADAM11 is also weakly detected in the heart, liver and testis.
Purified by Protein A chromatography
Fusion protein amino acids 243-441 (extracellular domain) of mouse ADAM11 (accession number Q9R1V4) produced recombinantly in E. Coli
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL550 Ex: 550 nm, Em: 575 nm
Does not cross-react with ADAM22
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
12 months from date of receipt
Shipped on ice packs
Disintegrin and metalloproteinase domain-containing protein 11 (ADAM 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC)