Products: Primary Antibodies

Anti-ADAM11 Antibody (N441/35)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-432
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-432
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG2b

Species Reactivity:

Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

ICC IHC WB

Target Description:

Disintegrin and metalloproteinase domain-containing protein 11, Metalloproteinase-Like, Disintegrin-Like, Cysteine-Rich Protein, or ADAM11 is encoded by the gene ADAM11 and a member of the ADAM (a disintegrin and metalloproteinase) family. ADAM11 is a single-pass type I membrane protein without catalytic metalloprotease-like properties. It is thought to be a ligand for integrin in the brain. ADAM11 is also weakly detected in the heart, liver and testis.

Immunogen:

Fusion protein amino acids 243-441 (extracellular domain) of mouse ADAM11 (also known as Disintegrin and metalloproteinase domain-containing protein 11, Metalloproteinase-like disintegrin-like and cysteine-rich protein, MDC and rCG_32562, accession number Q9R1V4)
Rat: 100% identity (199/199 amino acids identical)
Human: 99% identity (198/199 amino acids identical)
60% identity with ADAM22

Cross Reactivity:

Does not cross-react with ADAM22

Protein Name(s):

Disintegrin and metalloproteinase domain-containing protein 11 (ADAM 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC)

Gene Name(s):

Adam11 Mdc

Antibody Registry ID:

Purified: AB_2636850
TC Supernatant: AB_2531889


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Immunohistochemistry:
This antibody shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Molecular Weight:

75 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.