ICC IHC WB
Disintegrin and metalloproteinase domain-containing protein 11, Metalloproteinase-Like, Disintegrin-Like, Cysteine-Rich Protein, or ADAM11 is encoded by the gene ADAM11 and a member of the ADAM (a disintegrin and metalloproteinase) family. ADAM11 is a single-pass type I membrane protein without catalytic metalloprotease-like properties. It is thought to be a ligand for integrin in the brain. ADAM11 is also weakly detected in the heart, liver and testis.
Fusion protein amino acids 243-441 (extracellular domain) of mouse ADAM11 (also known as Disintegrin and metalloproteinase domain-containing protein 11, Metalloproteinase-like disintegrin-like and cysteine-rich protein, MDC and rCG_32562, accession number Q9R1V4)
Rat: 100% identity (199/199 amino acids identical)
Human: 99% identity (198/199 amino acids identical)
60% identity with ADAM22
Does not cross-react with ADAM22
Disintegrin and metalloproteinase domain-containing protein 11 (ADAM 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC)
TC Supernatant: AB_2531889
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.