Anti-VDAC1 Antibody FL490 Conjugate (N152B/23)

Name: Anti-VDAC1 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-204-FL490
Price: 486.0 USD
Availability: InStock

Our mouse VDAC1 FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N152B/23. It detects human, mouse, and rat VDAC1 and is purified by Protein A chromatography. Works in IHC, ICC.

Anti-VDAC1 Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-204-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

VDAC1

Scientific Background

Voltage-dependent anion-selective channel protein 1 or Outer Mitochondrial Membrane Protein Porin 1 is encoded by the gene VDAC1 and belongs to the mitochondrial porin family. VDAC1 is a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane and is also found on the plasma membrane of cells. VDAC1 can act as a scaffold for many proteins and allows for the passage of ions and metabolites, including ATP, through interactions within the pore. VDAC1 in the plasma membrane plays a role in the regulation of cell volume and apoptosis. VDAC1 is expressed in several tissues including heart, brain, liver and skeletal muscle. Diseases associated with VDAC1 include Influenza and Typhoid Fever.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N152B/23

Isotype

IgG2a

Applications

ICC, IHC

Host Species

Mouse

Gene Name

VDAC1 VDAC

Molecular Weight

30 kDa

Immunogen

Fusion protein amino acids 1-283 (full-length) of human VDAC1 (accession number P21796) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939756

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with VDAC2 or VDAC3 (based on KO validation results)

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Voltage-dependent anion-selective channel protein 1 (VDAC-1) (hVDAC1) (Outer mitochondrial membrane protein porin 1) (Plasmalemmal porin) (Porin 31HL) (Porin 31HM)

UniProt ID

P21796

Shipping

Shipped on ice packs

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Anti-VDAC1 Antibody FL490 Conjugate (N152B/23)

SKU: 75-204-FL490

Product Details

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