Anti-TRPML3/Mucolipin-3 Antibody FL490 Conjugate (N268/19)

Name: Anti-TRPML3/Mucolipin-3 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-283-FL490
Price: 486.0 USD
Availability: InStock

Our mouse TRPML3/Mucolipin-3 FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N268/19. It detects human, mouse, and rat TRPML3/Mucolipin-3 and is purified by Protein A chromatography. Works in ICC.

Anti-TRPML3/Mucolipin-3 Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-283-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

TRPML3/Mucolipin-3

Scientific Background

Mucolipin-3, Transient receptor potential cation channel, mucolipin subfamily, member 3 or TrpML3 is encoded by the gene MCOLN3. It is a member of the small family of the TRPML channels, a subgroup of the large protein family of TRP ion channels and acts as an inwardly rectifying cation channel. TrpML3 is found in the cochlea, olfactory kidney, lung and hair cells and strial cells of the inner ear. The protein localizes to the plasma membrane, endosomes, and lysosomes of cells. Mutations in this gene in mice result in auditory hair cell death and deafness

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N268/19

Isotype

IgG2a

Applications

ICC

Host Species

Mouse

Gene Name

MCOLN3

Molecular Weight

64 kDa

Immunogen

Synthetic peptide amino acids 269-285 (CKDWHVSGSIQKNTHYM, extracellular N-terminus) of human TRPML3 (accession number Q8TDD5)

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940008

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Mucolipin-3 (Transient receptor potential channel mucolipin 3) (TRPML3)

UniProt ID

Q8TDD5

Shipping

Shipped on ice packs

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Anti-TRPML3/Mucolipin-3 Antibody FL490 Conjugate (N268/19)

SKU: 75-283-FL490

Product Details

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