Our mouse TrpC5 FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N67/15. It detects guinea pig, human, mouse, and rat TrpC5 and is purified by Protein A chromatography. Works in IHC, ICC.
Short transient receptor potential channel 5 or TrpC5 is encoded by the gene TRPC5. TrpC5 belongs to the transient receptor family, a group of membrane bound ion channels that have a relatively non-selective permeability to cations, including sodium, calcium and magnesium. Apparent roles for Trpc5 include the regulation of neurite outgrowth. TrpC5 is found in the brain, developing fetal brain, CNS, and kidney. To date, TrpC5 functions in partnership with up to 60 proteins, including other TrpC members, IP3 receptors, NCS-1 and caveolin. Diseases associated with TrpC5 include Hypertrophic Pyloric Stenosis and Pyloric Stenosis
Purified by Protein A chromatography
Lot dependent: provided at 0.3-0.5 mg/mL
Monoclonal
N67/15
IgG2b
ICC, IHC
Mouse
TRPC5 TRP5
110 kDa
Synthetic peptide amino acids 827-845 (SKAESSSKRSFMGPSLKKL) of human TrpC5 (accession number Q9UL62)
Human
Guinea Pig, Human, Mouse, Rat
AB_2939388
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL490 Ex: 491 nm, Em: 515 nm
No cross-reactivity reported
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
12 months from date of receipt
Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (TRP-5) (hTRP-5) (hTRP5)
KO Validated