Primary Antibody
Guinea Pig, Human, Mouse, Rat
N67/15
ICC, IHC, IP, WB
Mouse
Purified by Protein A chromatography
TRPC5 TRP5
110 kDa
Adult rat hippocampal immunohistochemistry.
Product Specific References for Applications and Species
- Immunocytochemistry: Guinea Pig | Human | Mouse
- Immunohistochemistry: Guinea Pig | Human | Mouse | Rat
- Immunoprecipitation: Mouse
- Western Blot: Guinea Pig | Mouse | Rat
- Additional Publications: Unspecified
| Immunocytochemistry: Guinea Pig | ||
| PMID | Dilution | Publication |
| 21285322 | 1:500 | Qiu, J., et al. 2011. Guinea pig kisspeptin neurons are depolarized by leptin via activation of TRPC channels.. Endocrinology, 1503-1514. |
| Immunocytochemistry: Human | ||
| PMID | Dilution | Publication |
| 18832422 | 1:100 | Gomis, A., et al. 2008. Hypoosmotic- and pressure-induced membrane stretch activate TRPC5 channels.. The Journal of Physiology, 5633-5649. |
| Immunocytochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 36077460 | not listed | Amores-Bonet, L., et al. 2022. Interactions between the Polysialylated Neural Cell Adhesion Molecule and the Transient Receptor Potential Canonical Channels 1, 4, and 5 Induce Entry of Ca2+ …. International Journal of Molecular Science, 10027. |
| 30062674 | not listed | Park, S.E., et al. 2019. Contribution of zinc-dependent delayed calcium influx via TRPC5 in oxidative neuronal death and its prevention by novel TRPC antagonist. Molecular Neurobiology, 2822-2835. |
| 20978238 | 1:50 | Tian, D., et al. 2010. Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels.. Science Signaling, ra77. |
| Immunohistochemistry: Guinea Pig | ||
| PMID | Dilution | Publication |
| 24703699 | 1:500 | Qiu, J., et al. 2014. Insulin excites anorexigenic proopiomelanocortin neurons via activation of canonical transient receptor potential channels.. Cell Metabolism, 682-693. |
| Immunohistochemistry: Human | ||
| PMID | Dilution | Publication |
| 22025699 | 1:200 | Zimmermann, K., et al. 2011. Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the peripheral nervous system.. PNAS: USA, 18114-18119. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 36323817 | 1:500 | Su, C.L., et al. 2022. Wireless neuromodulation in vitro and in vivo by intrinsic TRPC-mediated magnetomechanical stimulation. Communications Biology, 1166. |
| 23188715 | not listed | Phelan, K.D., et al. 2013. Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms.. Molecular Pharmacology, 429-438. |
| 22037305 | 5ug/ml | Gilliam, J.C., et al. 2011. TRP channel gene expression in the mouse retina.. Vision Research, 2440-2452. |
| 19450521 | 1:500 | Riccio, A., et al. 2009. Essential role for TRPC5 in amygdala function and fear-related behavior.. Cell, 761-772. |
| Immunohistochemistry: Rat | ||
| PMID | Dilution | Publication |
| 35857479 | not listed | Westerling-Bui, A.D., et al. 2022. Transplanted Organoids Empower Human Preclinical Assessment of Drug Candidate for the Clinic. Science Advances, eabj5633. |
| 21179559 | not listed | Cvetkovic-Lopes, V., et al. 2010. Rat hypocretin/orexin neurons are maintained in a depolarized state by TRPC channels.. PLoS One, e15673. |
| Immunoprecipitation: Mouse | ||
| PMID | Dilution | Publication |
| 24599464 | 5ug | Riccio, A., et al. 2014. Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels.. Journal of Neuroscience, 3653-3667. |
| 19450521 | 5ug | Riccio, A., et al. 2009. Essential role for TRPC5 in amygdala function and fear-related behavior.. Cell, 761-772. |
| Western Blot: Guinea Pig | ||
| PMID | Dilution | Publication |
| 22744007 | not listed | Inoue, M., et al. 2012. Mechanisms and roles of muscarinic activation in guinea-pig adrenal medullary cells.. American Journal of Physiology-Cell Physiology, C635-C644. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 36077460 | not listed | Amores-Bonet, L., et al. 2022. Interactions between the Polysialylated Neural Cell Adhesion Molecule and the Transient Receptor Potential Canonical Channels 1, 4, and 5 Induce Entry of Ca2+ …. International Journal of Molecular Science, 10027. |
| 30062674 | not listed | Park, S.E., et al. 2019. Contribution of zinc-dependent delayed calcium influx via TRPC5 in oxidative neuronal death and its prevention by novel TRPC antagonist. Molecular Neurobiology, 2822-2835. |
| 30038709 | 1:200 | Cheung, S.Y., et al. 2018. TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A. Oncotarget, 29634-29643. |
| 29920354 | 1:500 | Lee, S.H., et al. 2018. Peripheral serotonin receptor 2B and transient receptor potential channel 4 mediate pruritus to serotonergic antidepressants in mice. Journal of Allergy and Clinical Immunology, 1349-1352. |
| 26133660 | not listed | Hong, C., et al. 2015. Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington''s disease.. Brain, 3030-3047. |
| 23858470 | 1:1000 | Park, S.H., et al. 2013. Leptin promotes K(ATP) channel trafficking by AMPK signaling in pancreatic β-cells.. PNAS: USA, 12673-12678. |
| 22547824 | 1:500 | Kaczmarek, J.S., et al. 2012. Calpain cleaves and activates the TRPC5 channel to participate in semaphorin 3A-induced neuronal growth cone collapse.. PNAS: USA, 7888-7892. |
| 22037305 | 2ug/ml | Gilliam, J.C., et al. 2011. TRP channel gene expression in the mouse retina.. Vision Research, 2440-2452. |
| 22031853 | not listed | Kim, E.Y., et al. 2011. Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen species.. American Journal of Physiology-Renal Physiology, F298-F307. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 35805070 | 1:1000 | Kim, E.Y., et al. 2022. TRPC6 Inactivation Reduces Albuminuria Induced by Protein Overload in Sprague Dawley Rats. Cells, 1985. |
| 32123821 | 1:200 | Hassanzadeh Khayyat, N., et al. 2019. TRPC6 inactivation does not protect against diabetic kidney disease in streptozotocin (STZ)‐treated Sprague‐Dawley rats. FASEB Bioadvances, 773-782. |
| 22457348 | not listed | Jeon, J.P., et al. 2012. A novel direct activation mechanism of TRPC4 and TRPC5 channels by selective Gαi subunits. Journal of Biological Chemistry, 17029-17039. |
| 22457348 | not listed | Jeon, J.P., et al. 2012. Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.. The Journal of Biological Chemistry, 17029-17039. |
| Additional Publications: Unspecified | ||
| PMID | Publication | |
| 20426773 | Salomonsson, M., et al. 2010. Na+-independent, nifedipine-resistant rat afferent arteriolar Ca2+ responses to noradrenaline: possible role of TRPC channels.. Acta Physiologica, 265-278. | |