Anti-TrpC5 Antibody (N67/15)

Name: Anti-TrpC5 Antibody
Brand: NeuroMab
SKU: 75-104
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet KO Validated

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Clonality

Monoclonal

Applications

IHC, IP, WB

Host Species

Mouse

Gene Name

TRPC5 TRP5

Molecular Weight

110 kDa

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Adult rat hippocampal immunohistochemistry.

Adult rat cerebellar immunohistochemistry.

Adult rat reticular thalamic nucleus immunohistochemistry.

Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and HEK-293 cells transiently transfected with TrpC5 and Kv2.1 plasmids and probed with N67/15 (left) or K89/34 (right) TC supe.

Immunoprecipitation analysis of TRPC5 protein in brain microsomes extracted from wild-type (WT) and TRPC5 knockout (KO) littermates. Courtesy of Dr. David Clapham (HHMI/Harvard Medical School).

Adult rat hippocampal immunohistochemistry.

Product Details

Target

TrpC5

Target Description

Short transient receptor potential channel 5 or TrpC5 is encoded by the gene TRPC5. TrpC5 belongs to the transient receptor family, a group of membrane bound ion channels that have a relatively non-selective permeability to cations, including sodium, calcium and magnesium. Apparent roles for Trpc5 include the regulation of neurite outgrowth. TrpC5 is found in the brain, developing fetal brain, CNS, and kidney. To date, TrpC5 functions in partnership with up to 60 proteins, including other TrpC members, IP3 receptors, NCS-1 and caveolin. Diseases associated with TrpC5 include Hypertrophic Pyloric Stenosis and Pyloric Stenosis

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N67/15

Isotype

IgG2b

Applications

IHC, IP, WB

Host Species

Mouse

Gene Name

TRPC5 TRP5

Molecular Weight

110 kDa

Antigen

Synthetic peptide amino acids 827-845 (SKAESSSKRSFMGPSLKKL) of human TrpC5 (also known as short transient receptor potential channel 5 and Htrp5, accession number Q9UL62); Mouse: 88% identity (16/18 amino acids identical); Rat: 88% identity (16/18 amino acids identical)

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2240979

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (TRP-5) (hTRP-5) (hTRP5)

UniProt Details

UniProt (Human): Q9UL62
UniProt (Immunogen Species): Q9UL62

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Anti-TrpC5 Antibody (N67/15)

Anti-TrpC5 Antibody
SKU: 75-104

Product Details

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Anti-TrpC5 Antibody (N67/15)

Anti-TrpC5 Antibody SKU: 75-104

Product Details

Anti-TrpC5 Antibody
SKU: 75-104