Short transient receptor potential channel 5 or TrpC5 is encoded by the gene TRPC5. TrpC5 belongs to the transient receptor family, a group of membrane bound ion channels that have a relatively non-selective permeability to cations, including sodium, calcium and magnesium. Apparent roles for Trpc5 include the regulation of neurite outgrowth. TrpC5 is found in the brain, developing fetal brain, CNS, and kidney. To date, TrpC5 functions in partnership with up to 60 proteins, including other TrpC members, IP3 receptors, NCS-1 and caveolin. Diseases associated with TrpC5 include Hypertrophic Pyloric Stenosis and Pyloric Stenosis
IHC, IP, WB
Synthetic peptide amino acids 827-845 (SKAESSSKRSFMGPSLKKL) of human TrpC5 (also known as short transient receptor potential channel 5 and Htrp5, accession number Q9UL62); Mouse: 88% identity (16/18 amino acids identical); Rat: 88% identity (16/18 amino acids identical)
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.