Anti-TrpC5 Antibody (N67/15)

Our Anti-TrpC5 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N67/15. It is KO validated, detects guinea pig, human, mouse, and rat TrpC5, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.



SKU: 75-104

Volume: 100 µL
1-2 business days
Price:
Sale price$319

Product Specific References for Applications and Species

Immunocytochemistry: Guinea Pig
PMID Dilution Publication
212853221:500Qiu, J., et al. 2011. Guinea pig kisspeptin neurons are depolarized by leptin via activation of TRPC channels.. Endocrinology, 1503-1514.
Immunocytochemistry: Human
PMID Dilution Publication
188324221:100Gomis, A., et al. 2008. Hypoosmotic- and pressure-induced membrane stretch activate TRPC5 channels.. The Journal of Physiology, 5633-5649.
Immunocytochemistry: Mouse
PMID Dilution Publication
36077460not listedAmores-Bonet, L., et al. 2022. Interactions between the Polysialylated Neural Cell Adhesion Molecule and the Transient Receptor Potential Canonical Channels 1, 4, and 5 Induce Entry of Ca2+ …. International Journal of Molecular Science, 10027.
30062674not listedPark, S.E., et al. 2019. Contribution of zinc-dependent delayed calcium influx via TRPC5 in oxidative neuronal death and its prevention by novel TRPC antagonist. Molecular Neurobiology, 2822-2835.
209782381:50Tian, D., et al. 2010. Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels.. Science Signaling, ra77.
Immunohistochemistry: Guinea Pig
PMID Dilution Publication
247036991:500Qiu, J., et al. 2014. Insulin excites anorexigenic proopiomelanocortin neurons via activation of canonical transient receptor potential channels.. Cell Metabolism, 682-693.
Immunohistochemistry: Human
PMID Dilution Publication
220256991:200Zimmermann, K., et al. 2011. Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the peripheral nervous system.. PNAS: USA, 18114-18119.
Immunohistochemistry: Mouse
PMID Dilution Publication
363238171:500Su, C.L., et al. 2022. Wireless neuromodulation in vitro and in vivo by intrinsic TRPC-mediated magnetomechanical stimulation. Communications Biology, 1166.
23188715not listedPhelan, K.D., et al. 2013. Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms.. Molecular Pharmacology, 429-438.
220373055ug/mlGilliam, J.C., et al. 2011. TRP channel gene expression in the mouse retina.. Vision Research, 2440-2452.
194505211:500Riccio, A., et al. 2009. Essential role for TRPC5 in amygdala function and fear-related behavior.. Cell, 761-772.
Immunohistochemistry: Rat
PMID Dilution Publication
35857479not listedWesterling-Bui, A.D., et al. 2022. Transplanted Organoids Empower Human Preclinical Assessment of Drug Candidate for the Clinic. Science Advances, eabj5633.
21179559not listedCvetkovic-Lopes, V., et al. 2010. Rat hypocretin/orexin neurons are maintained in a depolarized state by TRPC channels.. PLoS One, e15673.
Immunoprecipitation: Mouse
PMID Dilution Publication
245994645ugRiccio, A., et al. 2014. Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels.. Journal of Neuroscience, 3653-3667.
194505215ugRiccio, A., et al. 2009. Essential role for TRPC5 in amygdala function and fear-related behavior.. Cell, 761-772.
Western Blot: Guinea Pig
PMID Dilution Publication
22744007not listedInoue, M., et al. 2012. Mechanisms and roles of muscarinic activation in guinea-pig adrenal medullary cells.. American Journal of Physiology-Cell Physiology, C635-C644.
Western Blot: Mouse
PMID Dilution Publication
36077460not listedAmores-Bonet, L., et al. 2022. Interactions between the Polysialylated Neural Cell Adhesion Molecule and the Transient Receptor Potential Canonical Channels 1, 4, and 5 Induce Entry of Ca2+ …. International Journal of Molecular Science, 10027.
30062674not listedPark, S.E., et al. 2019. Contribution of zinc-dependent delayed calcium influx via TRPC5 in oxidative neuronal death and its prevention by novel TRPC antagonist. Molecular Neurobiology, 2822-2835.
300387091:200Cheung, S.Y., et al. 2018. TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A. Oncotarget, 29634-29643.
299203541:500Lee, S.H., et al. 2018. Peripheral serotonin receptor 2B and transient receptor potential channel 4 mediate pruritus to serotonergic antidepressants in mice. Journal of Allergy and Clinical Immunology, 1349-1352.
26133660not listedHong, C., et al. 2015. Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington''s disease.. Brain, 3030-3047.
238584701:1000Park, S.H., et al. 2013. Leptin promotes K(ATP) channel trafficking by AMPK signaling in pancreatic β-cells.. PNAS: USA, 12673-12678.
225478241:500Kaczmarek, J.S., et al. 2012. Calpain cleaves and activates the TRPC5 channel to participate in semaphorin 3A-induced neuronal growth cone collapse.. PNAS: USA, 7888-7892.
220373052ug/mlGilliam, J.C., et al. 2011. TRP channel gene expression in the mouse retina.. Vision Research, 2440-2452.
22031853not listedKim, E.Y., et al. 2011. Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen species.. American Journal of Physiology-Renal Physiology, F298-F307.
Western Blot: Rat
PMID Dilution Publication
358050701:1000Kim, E.Y., et al. 2022. TRPC6 Inactivation Reduces Albuminuria Induced by Protein Overload in Sprague Dawley Rats. Cells, 1985.
321238211:200Hassanzadeh Khayyat, N., et al. 2019. TRPC6 inactivation does not protect against diabetic kidney disease in streptozotocin (STZ)‐treated Sprague‐Dawley rats. FASEB Bioadvances, 773-782.
22457348not listedJeon, J.P., et al. 2012. A novel direct activation mechanism of TRPC4 and TRPC5 channels by selective Gαi subunits. Journal of Biological Chemistry, 17029-17039.
22457348not listedJeon, J.P., et al. 2012. Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.. The Journal of Biological Chemistry, 17029-17039.
Additional Publications: Unspecified
PMID Publication
20426773Salomonsson, M., et al. 2010. Na+-independent, nifedipine-resistant rat afferent arteriolar Ca2+ responses to noradrenaline: possible role of TRPC channels.. Acta Physiologica, 265-278.

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