Anti-THIK-2 Antibody Biotin Conjugate (N468/37)

Name: Anti-THIK-2 Antibody Biotin Conjugate
Brand: NeuroMab
SKU: 75-462-BTN
Price: 543.0 USD
Availability: InStock

Our mouse THIK-2 biotin conjugate monoclonal antibody from NeuroMab is produced in-house from clone N468/37. It detects mouse and rat THIK-2 and is purified by Protein A chromatography. Works in ELISA, IHC, ICC.

Anti-THIK-2 Antibody Biotin Conjugate

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Species Reactivity

Mouse, Rat

Applications

ELISA, ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Carrier-Free

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Data Sheet

SKU: 75-462-BTN

Volume: 200 µL

Variant

Price:

$543.00

Quantity:

Ships: 1-5 business days

Product Details

Target

THIK-2

Scientific Background

Potassium two pore domain channel subfamily K member 12 is encoded by the gene KCNK12. KCNK12 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK12 has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity. KCNK12 is highly expressed in the brain. Diseases associated with KCNK12 include Skin Angiosarcoma and Birk-Barel Syndrome.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N468/37

Isotype

IgG1

Applications

ELISA, ICC, IHC

Host Species

Mouse

Gene Name

Kcnk12 mntk1

Molecular Weight

47 kDa

Immunogen

Fusion Protein Amino acids 313-408 (cytoplasmic C-terminus) of mouse THIK-2 (accession number Q76M80) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

Biotin

Specificity

No cross-reactivity reported

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

K2p12.1; THIK-2; THIK2; Potassium channel subfamily K member 12; Tandem pore domain halothane-inhibitedpotassium channel 2; potassium channel; Kcnk12; subfamily K; MNTK1; member 12; tandem pore domain potassium channel THIK-2

UniProt ID

Q76M80
UniProt Summary: K(+) channel subunit that may homo- and heterodimerize to form functional channels with distinct regulatory and gating properties. Can heterodimerize with KCNK13 subunit to conduct K(+) outward rectifying currents at the plasma membrane. The homodimers are mainly retained in the endoplasmic reticulum compartment and may be targeted to the cell surface upon phosphorylation or other activation signals yet to be elucidated.

NCBI Gene ID

56660

Shipping

Shipped on ice packs

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Anti-THIK-2 Antibody Biotin Conjugate (N468/37)

SKU: 75-462-BTN

Product Details

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