Adult rat hippocampus (left) and cerebellum (right) immunohistochemistry.
Anti-THIK-2 K+ Channel Antibody
Bulk Order Anti-THIK-2 K+ Channel Antibody
Potassium two pore domain channel subfamily K member 12 is encoded by the gene KCNK12. KCNK12 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK12 has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity. KCNK12 is highly expressed in the brain. Diseases associated with KCNK12 include Skin Angiosarcoma and Birk-Barel Syndrome.
Purified by Protein A chromatography
Fusion protein amino acids 313-408 (cytoplasmic C-terminus) of mouse THIK-2 (accession number Q76M80) produced recombinantly in E. Coli
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
No cross-reactivity reported
Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from date of receipt
Shipped on ice packs
THIK-2 (Potassium channel subfamily K member 12) (Tandem pore domain halothane-inhibitedpotassium channel 2) (Kcnk12) (MNTK1)