Anti-Slo2.1/Slick K+ Channel Antibody (N11/33)

Name: Anti-Slo2.1/Slick K+ Channel Antibody
Brand: NeuroMab
SKU: 75-055
Price: 337.0 USD
Availability: InStock

Our mouse Slo2.1/Slick K+ channel monoclonal antibody from NeuroMab is produced in-house from clone N11/33. It detects mouse, rat, and Xenopus Slo2.1/Slick K+ channel and is purified by Protein A chromatography. KO validated. Works in WB, IHC, ICC, IP, ELISA, EM.

Immunoblot against brain membranes from adult rat (RBM) or from Slo2.1 knockout (MBM-Slo2.1 KO) or wild-type (MBM-WT) mice probed with N11/33 (left) or N52A/42 (right) TC supe. Mouse brains courtesy of Chris Lingle (Washington University).

Adult rat hippocampal immunohistochemistry.

Adult rat whole brain immunohistochemistry.

Immunoblot against brain membranes from adult rat (RBM) or from Slo2.1 knockout (MBM-Slo2.1 KO) or wild-type (MBM-WT) mice probed with N11/33 (left) or N52A/42 (right) TC supe. Mouse brains courtesy of Chris Lingle (Washington University).

Click on image to zoom

Species Reactivity

Mouse, Rat, Xenopus

Applications

ELISA, EM, ICC, IHC, IP, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-055

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Slo2.1/Slick K+ channel

Scientific Background

Potassium sodium-activated channel subfamily T member 2 is encoded by the gene KCNT2. KCNT2 is a member of the potassium channel family, calcium-activated (TC 1.A.1.3) subfamily, KCa4.2/KCNT2 sub-subfamily. KCNT2 is an outward rectifying potassium channel which produces rapidly activating outward rectifying K+ currents. KCNT2 is expressed in the brain and skin. Diseases associated with KCNT2 include Early Infantile Epileptic Encephalopathy 57 and Bulbar Polio.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N11/33

Isotype

IgG1

Applications

ELISA, EM, ICC, IHC, IP, WB

Host Species

Mouse

Gene Name

Kcnt2

Molecular Weight

140 kDa

Immunogen

Fusion protein amino acids 564-624 of mouse Slo2.1 (accession number XP_920840) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Mouse, Rat, Xenopus

Antibody Registry ID

AB_2296599

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4

Dilution Ranges

WB: 1:1000
IHC: 1:250
ICC: 1:100

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Potassium channel, subfamily T, member 2

UniProt ID

D3Z649

Shipping

Shipped on ice packs

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Anti-Slo2.1/Slick K+ Channel Antibody (N11/33)

SKU: 75-055

Product Details

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