Anti-SAP97 Antibody FL490 Conjugate (K64/15)

Name: Anti-SAP97 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-030-FL490
Price: 486.0 USD
Availability: InStock

Our mouse SAP97 FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone K64/15. It detects human, mouse, rabbit, and rat SAP97 and is purified by Protein A chromatography. KO validated. Works in IHC.

Anti-SAP97 Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rabbit, Rat

Applications

IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-030-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

SAP97

Scientific Background

Synapse-associated protein 97, Discs Large MAGUK Scaffold Protein 1 or SAP97 is encoded by the gene DLG1. SAP97 is a member of the MAGUK (membrane-associated guanylate kinase) protein family. It is a multi-domain scaffolding protein which serves to recruit receptors channels and other signaling molecules to the plasma membrane. SAP97 is expressed in heart, lung, epithelial cells and brain. SAP97 may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Diseases associated with DLG1 include Mayer-Rokitansky-Kuster-Hauser Syndrome and Depression.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

K64/15

Isotype

IgG1

Applications

IHC

Host Species

Mouse

Gene Name

Dlg1 Dlgh1

Molecular Weight

130 kDa

Immunogen

Fusion protein amino acids 1-104 (N-terminus) of rat SAP97 (accession number Q62696) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rabbit, Rat

Antibody Registry ID

AB_2939176

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity against PSD-95, Chapsyn-110 and SAP102 expressed in transfected cells

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)

UniProt ID

Q62696

Shipping

Shipped on ice packs

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Anti-SAP97 Antibody FL490 Conjugate (K64/15)

SKU: 75-030-FL490

Product Details

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