Synapse-associated protein 97, Discs Large MAGUK Scaffold Protein 1 or SAP97 is encoded by the gene DLG1. SAP97 is a member of the MAGUK (membrane-associated guanylate kinase) protein family. It is a multi-domain scaffolding protein which serves to recruit receptors channels and other signaling molecules to the plasma membrane. SAP97 is expressed in heart, lung, epithelial cells and brain. SAP97 may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Diseases associated with DLG1 include Mayer-Rokitansky-Kuster-Hauser Syndrome and Depression.
IHC, IP, WB
Fusion protein amino acids 1-104 (N-terminus) of rat SAP97 (also known as synapse-associated protein 97 and disks large homolog 1, accession number Q62696); Human: 84% identity (87/104 amino acids identical); Mouse: 90% identity (94/104 amino acids identical)
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.