Synapse-associated protein 97, Discs Large MAGUK Scaffold Protein 1 or SAP97 is encoded by the gene DLG1. SAP97 is a member of the MAGUK (membrane-associated guanylate kinase) protein family. It is a multi-domain scaffolding protein which serves to recruit receptors channels and other signaling molecules to the plasma membrane. SAP97 is expressed in heart, lung, epithelial cells and brain. SAP97 may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Diseases associated with DLG1 include Mayer-Rokitansky-Kuster-Hauser Syndrome and Depression.
IHC, IP, WB
Fusion protein amino acids 1-104 (N-terminus) of rat SAP97 (also known as synapse-associated protein 97 and disks large homolog 1, accession number Q62696); Human: 84% identity (87/104 amino acids identical); Mouse: 90% identity (94/104 amino acids identical)
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity against PSD-95, Chapsyn-110 and SAP102 expressed in transfected cells
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from opening
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)