Anti-SAP102 Antibody FL490 Conjugate (N19/2)

Name: Anti-SAP102 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-058-FL490
Price: 486.0 USD
Availability: InStock

Our mouse SAP102 FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N19/2. It detects human, mouse, rabbit, and rat SAP102 and is purified by Protein A chromatography. KO validated. Works in IHC, ICC.

Anti-SAP102 Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rabbit, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-058-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

SAP102

Scientific Background

Synapse-Associated Protein 102, Disks large homolog 3(DLG3) or SAP102 MAGUK scaffold protein is encoded by the gene DLG3. SAP102 is a member of the MAGUK (membrane-associated guanylate kinase) protein family. SAP102 can bind to a number of adhesion molecules and receptors, including NMDA receptors and acts as a scaffold protein to mediate synaptic signaling. This protein plays a role in learning and memory and appears to be required for learning. Mutations in this gene have been associated with X-linked cognitive disability.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N19/2

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Dlg3 Dlgh3

Molecular Weight

105 kDa

Immunogen

Fusion protein amino acids 1-120 of rat SAP102 (accession number Q62936) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rabbit, Rat

Antibody Registry ID

AB_2939252

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity against other MAGUK family membersPSD-95, SAP97, Chapsyn-110

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Disks large homolog 3 (PSD-95/SAP90-related protein 1) (Synapse-associated protein 102) (SAP-102) (SAP102)

UniProt ID

Q62936

Shipping

Shipped on ice packs

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Anti-SAP102 Antibody FL490 Conjugate (N19/2)

SKU: 75-058-FL490

Product Details

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