Anti-SAP102 Antibody (N19/2)

Our Anti-SAP102 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N19/2. It is KO validated, detects human, mouse, and rat SAP102, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.



SKU: 75-058

Volume: 100 µL
1-2 business days
Price:
Sale price$319.00

Product Specific References for Applications and Species

Immunocytochemistry: Mouse
PMID Dilution Publication
29415226not listedMohan, V., et al. 2019. Temporal regulation of dendritic spines through NrCAM-Semaphorin3F receptor signaling in developing cortical pyramidal neurons. Cerebral Cortex, 963-977.
222464371:1000Zheng, S., et al. 2012. PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2. Nature Neuroscience, 381-388.
Immunocytochemistry: Rat
PMID Dilution Publication
385824511:1000-1:5000Kunde, SA, et al. 2024. JNK activity modulates postsynaptic scaffold protein SAP102 and kainate receptor dynamics in dendritic spines. The Journal of Biological Chemistry, 107263.
266651641:50Tao-Cheng, J.H., et al. 2015. Depolarization of Hippocampal Neurons Induces Formation of Nonsynaptic NMDA Receptor Islands Resembling Nascent Postsynaptic Densities.. eNeuro, .
23904596not listedOku, Y., et al. 2013. AGAP3 and Arf6 regulate trafficking of AMPA receptors and synaptic plasticity.. Journal of Neuroscience, 12586-12598.
215436101:500Sun, Q., et al. 2011. PSD-95 and PSD-93 play critical but distinct roles in synaptic scaling up and down.. Journal of Neuroscience, 6800-6808.
21048125not listedSteinmetz, C.C., et al. 2010. Tumor necrosis factor-α signaling maintains the ability of cortical synapses to express synaptic scaling.. Journal of Neuroscience, 14685-14690.
20096331not listedPetralia, R.S., et al. 2010. Organization of NMDA receptors at extrasynaptic locations.. Neuroscience, 68-87.
Immunohistochemistry: Mouse
PMID Dilution Publication
300785781:250Zhu, F., et al. 2018. Architecture of the mouse brain synaptome. Neuron, 781-799.
254291501:500Williams, L.E., et al. 2014. Regulation of hippocampal synaptic strength by glial xCT.. Journal of Neuroscience, 16093-16102.
253527481:200de Andrade, G.B., et al. 2014. Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina.. Molecular Vision, 1422-33.
227457501:100Lauks, J., et al. 2012. Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin.. PLoS One, e39420.
219404421:500Mondin, M., et al. 2011. Neurexin-neuroligin adhesions capture surface-diffusing AMPA receptors through PSD-95 scaffolds.. Journal of Neuroscience, 13500-13515.
Immunohistochemistry: Rabbit
PMID Dilution Publication
275581971:500Vila, A., et al. 2017. Membrane‐associated guanylate kinase scaffolds organize a horizontal cell synaptic complex restricted to invaginating contacts with photoreceptors. Journal of Comparative Neurology, 850-867.
Immunohistochemistry: Rat
PMID Dilution Publication
20096331not listedPetralia, R.S., et al. 2010. Organization of NMDA receptors at extrasynaptic locations.. Neuroscience, 68-87.
ImmunoGold Labeling: Rat
PMID Dilution Publication
291346551:20Suzuki, T., et al. 2018. Protein components of post‐synaptic density lattice, a backbone structure for type I excitatory synapses. Journal of Neurochemistry, 390-407.
262159191:10Farley, M.M., et al. 2015. Electron tomographic structure and protein composition of isolated rat cerebellar, hippocampal and cortical postsynaptic densities.. Neuroscience, 286-301.
Immunoprecipitation: Mouse
PMID Dilution Publication
197266511ug/mlFan, J., et al. 2009. Interaction of postsynaptic density protein-95 with NMDA receptors influences excitotoxicity in the yeast artificial chromosome mouse model of Huntington''s disease.. Journal of Neuroscience, 10928-10938.
Western Blot: Human
PMID Dilution Publication
385824511:1000-1:5000Kunde, SA, et al. 2024. JNK activity modulates postsynaptic scaffold protein SAP102 and kainate receptor dynamics in dendritic spines. The Journal of Biological Chemistry, 107263.
26595655not listedJang, S., et al. 2016. Synaptic adhesion molecule IgSF11 regulates synaptic transmission and plasticity. Nature Neuroscience, 84-93.
Western Blot: Mouse
PMID Dilution Publication
364290741:500Flores-Muñoz, C., et al. 2022. The Long-Term Pannexin 1 Ablation Produces Structural And Functional Modifications In Hippocampal Neurons. Cells, 3646.
34613779not listedBan, Y., et al. 2021. Prickle promotes the formation and maintenance of glutamatergic synapses by stabilizing the intercellular planar cell polarity complex. Science Advances, .
33125726not listedBriševac, D., et al. 2021. The small GTPase Arf6 is dysregulated in a mouse model for fragile X syndrome. Journal of Neurochemistry, 666-683.
33229412not listedPandian, S., et al. 2020. Myosin va brain-specific mutation alters mouse behavior and disrupts hippocampal synapses. eNeuro, .
33198813not listedArsenault, D., et al. 2020. Sex-dependent alterations in the physiology of entorhinal cortex neurons in old heterozygous 3xTg-AD mice. Biology of Sex Difference, 63.
31849613not listedGutierrez, D.A., et al. 2019. c-Abl Deficiency Provides Synaptic Resiliency Against Aβ-Oligomers. Frontiers in Cellular Neuroscience, 526.
309460071:2000Koster, K.P., et al. 2019. Developmental NMDA receptor dysregulation in the infantile neuronal ceroid lipofuscinosis mouse model. Elife, e40316.
30936304not listedWon, S., et al. 2019. The STEP61 interactome reveals subunit-specific AMPA receptor binding and synaptic regulation. PNAS, 8028-8037.
30451289not listedVaden, J.H., et al. 2019. Chronic over-expression of ubiquitin impairs learning, reduces synaptic plasticity, and enhances GRIA receptor turnover in mice. Journal of Neurochemistry, 386-399.
29415226not listedMohan, V., et al. 2019. Temporal regulation of dendritic spines through NrCAM-Semaphorin3F receptor signaling in developing cortical pyramidal neurons. Cerebral Cortex, 963-977.
30586380not listedFavaro, P.D., et al. 2018. An opposing function of paralogs in balancing developmental synapse maturation. Plos Biology, e2006838.
300785781:1000Zhu, F., et al. 2018. Architecture of the mouse brain synaptome. Neuron, 781-799.
29995933not listedGupta, P., et al. 2018. SAP97 regulates behavior and expression of schizophrenia risk enriched gene sets in mouse hippocampus. PLoS One, e0200477.
29429936not listedMatt, L., et al. 2018. α-actinin anchors PSD-95 at postsynaptic sites. Neuron, 1094-1109.
289048541:2000Kunde, S.A., et al. 2017. Protein kinase C regulates AMPA receptor auxiliary protein Shisa9/CKAMP 44 through interactions with neuronal scaffold PICK 1. FEBS Open Bio, 1234-1245.
280774871:1000Shukla, A., et al. 2017. Calcium‐permeable AMPA receptors and silent synapses in cocaine‐conditioned place preference.. The EMBO journal, 458-474.
27457929not listedWon, S., et al. 2016. PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61.. PNAS: USA, E4736-E4744.
271346851:2000Sinclair, D., et al. 2016. Effects of sex and DTNBP1 (dysbindin) null gene mutation on the developmental GluN2B-GluN2A switch in the mouse cortex and hippocampus. Journal of Neurodevelopmental Disorders, 14.
259341011 : 100Farzana, F., et al. 2016. Neurobeachin Regulates Glutamate- and GABA-Receptor Targeting to Synapses via Distinct Pathways.. Molecular Neurobiology, 2112-2123.
291242161:2000Rizzi, S., et al. 2015. Identification of potential novel interaction partners of the sodium-activated potassium channels Slick and Slack in mouse brain. Biochemistry and Biophysics Reports, 291-298.
260058511:1000Shin, S., et al. 2015. mGluR5 in the nucleus accumbens is critical for promoting resilience to chronic stress. Nature Neuroscience, 1017-1024.
25505322not listedFortin, D.A., et al. 2015. Live imaging of endogenous PSD-95 using ENABLED: a conditional strategy to fluorescently label endogenous proteins.. Journal of Neuroscience, 16698-16712.
247955611:1000Lugo, J.N., et al. 2014. Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins.. Frontiers in Molecular Neuroscience, 27.
23946397not listedBonnet, S.A., et al. 2013. Synaptic state-dependent functional interplay between postsynaptic density-95 and synapse-associated protein 102.. Journal of Neuroscience, 13398-13409.
237198051 : 1000Hoy, J.L., et al. 2013. Neuroligin1 drives synaptic and behavioral maturation through intracellular interactions.. Journal of Neuroscience, 9364-9384.
227457501:1000Lauks, J., et al. 2012. Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin.. PLoS One, e39420.
223692341:1000Wilke, S.A., et al. 2012. NeuroD2 regulates the development of hippocampal mossy fiber synapses.. Neural Development, 9.
222464371:1000Zheng, S., et al. 2012. PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2. Nature Neuroscience, 381-388.
21808020not listedEtherton, M., et al. 2011. Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function.. PNAS: USA, 13764-13769.
19679819not listedChaudhury, A., et al. 2009. Role of PSD95 in membrane association and catalytic activity of nNOSalpha in nitrergic varicosities in mice gut.. The American Journal of Gastrointestinal and Liver Physiology, G806-13.
19406213not listedGarside, M.L., et al. 2009. Molecular interactions of the plasma membrane calcium ATPase 2 at pre- and post-synaptic sites in rat cerebellum.. Neuroscience, 383-395.
Western Blot: Rat
PMID Dilution Publication
385824511:1000-1:5000Kunde, SA, et al. 2024. JNK activity modulates postsynaptic scaffold protein SAP102 and kainate receptor dynamics in dendritic spines. The Journal of Biological Chemistry, 107263.
30067114not listedLiu, M., et al. 2018. SAP102 regulates synaptic AMPAR function through a CNIH-2-dependent mechanism. Journal of Neurophysiology, 1578-1586.
28283559not listedLiu, S., et al. 2017. A rare variant identified within the GluN2B C-terminus in a patient with autism affects NMDA receptor surface expression and spine density. . Journal of Neuroscience, 4093-4102.
27457929not listedWon, S., et al. 2016. PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61.. PNAS: USA, E4736-E4744.
262478612ug/mlLevy, J.M., et al. 2015. Synaptic Consolidation Normalizes AMPAR Quantal Size following MAGUK Loss.. Neuron, 534-548.
247803801:1000Bernard, P.B., et al. 2014. Necessary, but not sufficient: insights into the mechanisms of mGluR mediated long-term depression from a rat model of early life seizures.. Neuropharmacology, 1-12.
23486974not listedMurata, Y., et al. 2013. Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway.. Journal of Neuroscience, 5040-5052.
21209193not listedChen, B.S., et al. 2011. NMDA receptor-dependent regulation of dendritic spine morphology by SAP102 splice variants.. Journal of Neuroscience, 89-96.
17670980not listedAl-Hallaq, R.A., et al. 2007. NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus.. Journal of Neuroscience, 8334-8343.
Additional Publications: Unspecified
PMID Publication
21946113Gardoni, F., et al. 2011. Effect of rasagiline on the molecular composition of the excitatory postsynaptic density.. European Journal of Pharmacology, 458-463.
21525273Chen, X., et al. 2011. PSD-95 is required to sustain the molecular organization of the postsynaptic density. Journal of Neuroscience, 6329-6338.

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