Synapse-Associated Protein 102, Disks large homolog 3(DLG3) or SAP102 MAGUK scaffold protein is encoded by the gene DLG3. SAP102 is a member of the MAGUK (membrane-associated guanylate kinase) protein family. SAP102 can bind to a number of adhesion molecules and receptors, including NMDA receptors and acts as a scaffold protein to mediate synaptic signaling. This protein plays a role in learning and memory and appears to be required for learning. Mutations in this gene have been associated with X-linked cognitive disability.
Purified
1 mg/mL
Monoclonal
N19/2
IgG1
IHC, IP, WB
Mouse
Dlg3 Dlgh3
105 kDa
Fusion protein amino acids 1-120 of rat SAP102 (accession number Q62936); Human: 98% identity (117/120 amino acids identical); Mouse: 98% identity (118/120 amino acids identical)
Human, Mouse, Rat
AB_2261666
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity against other MAGUK family membersPSD-95, SAP97, Chapsyn-110
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from opening
Disks large homolog 3 (PSD-95/SAP90-related protein 1) (Synapse-associated protein 102) (SAP-102) (SAP102)
