Anti-Pan-synuclein Antibody

Name: Anti-Pan-synuclein Antibody
Brand: Biosensis
SKU: S-044-100
Price: 337.0 USD
Availability: InStock

Our Anti-Pan-synuclein sheep polyclonal primary antibody detects human and rat Pan-synuclein, and is affinity-purified. It is validated for use in IHC-Frozen, WB.

Dot blot of human synuclein proteins (20 ng/dot) with S-044-100, diluted to 1 µg/mL.

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Species Reactivity

Human, Rat

Applications

IHC, WB

Host Species

Sheep

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Data Sheet

SKU: S-044-100

Volume/Size: 100 µg

Variant

Price:

$337.00

Quantity:

Product Details

Target

Pan-synuclein

Scientific Background

Detects human alpha-, beta-, and gamma synuclein proteins. A family of homologous proteins known as alpha-, beta-, and gamma-synuclein are abundantly expressed in brain, especially in the presynaptic terminal of neurons. Although the precise function of these proteins remains unknown, alpha-synuclein has been implicated in synaptic plasticity associated with avian song learning as well as in the pathogenesis of Parkinson's disease (PD), dementia with LBs (DLB), some forms of Alzheimer's disease (AD), and multiple system atrophy (MSA).

Format

Affinity-purified

Clonality

Polyclonal

Isotype

IgG

Applications

IHC, WB

Host Species

Sheep

Immunogen

A synthetic peptide (AKEGVVAAAEKTKQGV) as a consensus part of human alpha-, beta-, and gamma synuclein proteins conjugated to diphteria toxoid has been used as the immunogen.

Immunogen Species

Human

Species Reactivity

Human, Rat

Storage

Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

Physical State

Lyophilized

Production Notes

Affinity purified and dialysed against PBS. Contains 0.02% sodium azide.

Dilution Ranges

WB: 1 µg/mL
IHC: 3 µg/mL

Conjugate

Unconjugated

Specificity

Overlap specific immunohistochemical staining of alpha-, beta- and gamma synucleins This antiserum recognizes human and rat alpha-, beta- and gamma synucleins.

Usage Statement

For research use only.

Country of Origin

United States

Expiration

12 months after date of receipt (unopened vial).

UniProt ID

P37840; Q16143; O76070

Shipping

25°C (ambient)

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Anti-Pan-synuclein Antibody

SKU: S-044-100

Product Details

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