Anti-Myelin Basic Protein (MBP) Antibody Biotin Conjugate

Name: Anti-Myelin Basic Protein (MBP) Antibody Biotin Conjugate
Brand: Antibodies Incorporated
SKU: RP-4015-BTN
Price: 543.0 USD
Availability: InStock

Our rabbit Mylein Basic Protein biotin conjugate polyclonal antibody from Antibodies Incorporated is produced in-house from clone . It detects human Mylein Basic Protein And is purified by Protein A chromatography. Works in ELISA, IHC, ICC, WB.

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Species Reactivity

Human

Applications

ELISA, ICC, IHC, WB

Host Species

Rabbit

Conjugates and Formulations

Unconjugated

490

550

594

650

Carrier-Free

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SKU: RP-4015-BTN

Volume: 200 µL

Variant

Price:

$543.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Mylein Basic Protein

Scientific Background

Myelin Basic Protein (MBP) a 19.6 kDa highly basic protein is a major constituent of central nervous system (CNS). This protein is synthesized by oligodendrocyte and Schwann cells. MBP, Proteolipid (PLP), myelin oligodendrocyte glycoprotein (MOG) are primary encephaltogenic target antigens in multiple sclerosis. The gene for MBP is on chromosome 18; the protein localizes to CNS and to various cells of the hematopoietic system. MBP is expressed in oligodendrocyte, myelin of white matter, spinal cord and in peripheral nerves. This antibody stains white matter and oligodendrocyte.

Format

Purified by Protein A Chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, ICC, IHC, WB

Host Species

Rabbit

Gene Name

MBP

Molecular Weight

20 kDa

Immunogen Species

Human

Species Reactivity

Human

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Prepared from pooled rabbit serum by Protein A affinity chromatography and conjugation of purified antibody.

Buffer

PBS with 0.09% azide

Conjugate

Biotin

Specificity

No cross-reactivity reported

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

GDB antibody; MBP; Golli MBP antibody; Myelin membrane encephalitogenic protein; Golli MBP myelin basic protein antibody; Myelin A1 protein; Hemopoietic MBP antibody; HMBPR antibody; HUGO antibody; MBP antibody; MBP_CAVPO antibody; MBP_HUMAN antibody; MGC99675 antibody; MLD antibody; Myelin A1 protein antibody; Myelin A1 Protein basic antibody; Myelin basic protein antibody; Myelin Deficient antibody; Myelin membrane encephalitogenic protein antibody; OTTHUMP00000163776 antibodym; OTTHUMP00000174387 antibody; OTTHUMP00000174388 antibody; SHI antibody; Shiverer antibody; SP antibody

UniProt ID

P02686
UniProt Summary: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.

NCBI Gene ID

4155

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Anti-Myelin Basic Protein (MBP) Antibody Biotin Conjugate

SKU: RP-4015-BTN

Product Details

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