Anti-Kv1.1 K+ Channel Antibody (BSA and Azide free) (K20/78)

Name: Anti-Kv1.1 K+ Channel Antibody (BSA and Azide free)
Brand: NeuroMab
SKU: 75-007-CF
Price: 486.0 USD
Availability: InStock

Our mouse Kv1.1 K+ channel carrier-free monoclonal antibody from NeuroMab is produced in-house from clone K20/78. It detects C. elegans, finch, human, mouse, rabbit, and rat Kv1.1 K+ channel and is purified by Protein A chromatography. KO validated. Works in WB, IHC, ICC, ELISA.

Anti-Kv1.1 K+ Channel Antibody (BSA and Azide free)

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Species Reactivity

C. elegans, Finch, Human, Mouse, Rabbit, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Biotin

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Data Sheet

KO Validated

SKU: 75-007-CF

Volume: 100 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Kv1.1 K+ channel

Scientific Background

Potassium Channel Kv1.1 or Kcna1 is a member of the Shaker potassium channel family. Kv1.1 is expressed in the brain, CNS and in the kidney. Potassium channels form homotetrameric and heterotetrameric channels in the membrane with various other related proteins, including KCNA2, KCNA4, KCNA5, KCNA6, KCNA7. Kv1.1 is involved with the regulation of cellular functions and the control of neuronal excitability. Mutations in Kv1.1 are associated with Episodic ataxia type 1 and epilepsy.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.6-1.0 mg/mL

Clonality

Monoclonal

Clone

K20/78

Isotype

IgG1

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Kcna1

Molecular Weight

85 kDa (major: mature glycosylation),65 kDa (minor: immature glycosylation)

Immunogen

Synthetic peptide amino acids 458-476 (cytoplasmic C-terminus) of rat Kv1.1 (EEDMNNSIAHYRQANIRTG; accession number P10499)

Immunogen Species

Rat

Species Reactivity

C. elegans, Finch, Human, Mouse, Rabbit, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Buffer

PBS

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Potassium voltage-gated channel subfamily A member 1 (RBKI) (RCK1) (Voltage-gated potassium channel subunit Kv1.1)

UniProt ID

P10499

Shipping

Shipped on ice packs

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Anti-Kv1.1 K+ Channel Antibody (BSA and Azide free) (K20/78)

SKU: 75-007-CF

Product Details

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