Anti-GABA-A-R-Pi Antibody (N431/64)

Name: Anti-GABA-A-R-Pi Antibody
Brand: NeuroMab
SKU: 75-419
Price: 337.0 USD
Availability: InStock

Our mouse GABA-A-R-Pi monoclonal antibody from NeuroMab is produced in-house from clone N431/64. It detects human and rat GABA-A-R-Pi and is purified by Protein A chromatography. Works in WB, ICC, ELISA.

Immunoblot against extracts of COS cells transiently transfected with untagged GABAARPi, GFP-tagged GABAARDelta or untagged Kv2.1 plasmid probed with N431/64 (left) or N86/8 (right) TC supe.

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Species Reactivity

Human, Rat

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-419

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

GABA-A-R-Pi

Scientific Background

Gamma-aminobutyric acid receptor subunit pi or GABA AR Pi is encoded by the gene GABRP. GABA A receptors are members of the Cys-loop family of ligand-gated ion channels. GABA AR pi is a subunit of the pentameric GABA receptors where GABA is the major inhibitory neurotransmitter in the vertebrate brain and mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel. GABA AR Pi has been found in tissues including the uterus, ovaries lung, thymus and prostate.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N431/64

Isotype

IgG2a

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

GABRP

Molecular Weight

45 kDa

Immunogen

Fusion protein amino acids 22-242 (extracellular N-terminus) of human GABA-A receptor Pi (accession number O00591) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Rat

Antibody Registry ID

AB_2532051

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Dilution Ranges

IHC: 1:100

Conjugate

Unconjugated

Specificity

Does not cross-react with GABAARDelta

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Gamma-aminobutyric acid receptor subunit pi (GABA(A) receptor subunit pi)

UniProt ID

O00591

Shipping

Shipped on ice packs

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Anti-GABA-A-R-Pi Antibody (N431/64)

SKU: 75-419

Product Details

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