Anti-Dopamine D2 Receptor Antibody (N186/29)

Name: Anti-Dopamine D2 Receptor Antibody
Brand: NeuroMab
SKU: 75-230
Price: 337.0 USD
Availability: InStock

Our mouse Dopamine D2 receptor monoclonal antibody from NeuroMab is produced in-house from clone N186/29. It detects mouse and rat Dopamine D2 receptor and is purified by Protein A chromatography. Works in IHC, ICC, ELISA.

Adult rat striatum immunohistochemistry.

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Species Reactivity

Mouse, Rat

Applications

ELISA, IHC

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-230

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Dopamine D2 receptor

Scientific Background

Dopamine D2 receptor is encoded by the gene DRD2. DRD2 is a member of the G-protein coupled receptor 1 family that also includes D1, D3, D4 and D5. This G-protein coupled receptor inhibits adenylyl cyclase activity. DRD2 is expressed in the brain, colon, testis, and skeletal muscle tissue. Diseases associated with DRD2 include cocaine dependence, pathological gambling, and delusional disorder.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N186/29

Isotype

IgG1

Applications

ELISA, IHC

Host Species

Mouse

Gene Name

Drd2

Molecular Weight

50 kDa

Immunogen

Fusion protein amino acids 211-374 (cytoplasmic, long form) of rat Dopamine D2 receptor (accession number P61169) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_11000721

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Reacts with both Long and Short formsDoes not cross-react with Dopamine D3 receptor

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

D(2) dopamine receptor (Dopamine D2 receptor)

UniProt ID

P61169

Shipping

Shipped on ice packs

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Anti-Dopamine D2 Receptor Antibody (N186/29)

SKU: 75-230

Product Details

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