Anti-DNMT3L Antibody FL594 Conjugate (N117/9)

Name: Anti-DNMT3L Antibody FL594 Conjugate
Brand: NeuroMab
SKU: 75-153-FL594
Price: 486.0 USD
Availability: InStock

Our mouse DNMT3L FL594 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N117/9. It detects human DNMT3L and is purified by Protein A chromatography. Works in ICC.

Anti-DNMT3L Antibody FL594 Conjugate

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Species Reactivity

Human

Applications

ICC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-153-FL594

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

DNMT3L

Scientific Background

DNA (cytosine-5)-methyltransferase 3-like or DNMT3L is encoded by the gene DNMT3L. DNMT3l is a nuclear, catalytically inactive, regulatory factor of DNA methyltransferases. DNMT3L mediates transcriptional repression through interaction with histone deacetylase 1. It is thought to be required for the establishment of maternal genomic imprints. DNMT3L is expressed in several tissues including testis, ovary, and thymus. Diseases associated with DNMT3L include Testicular Spermatocytic Seminoma and Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N117/9

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

DNMT3L

Molecular Weight

45 kDa

Immunogen

Fusion protein amino acids 1-387 (full-length) of human DNMT3L (accession number BAA95556) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human

Antibody Registry ID

AB_2939566

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

Specificity

No cross-reactivity against DNMT3A or DNMT3B

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

DNA (cytosine-5)-methyltransferase 3-like

UniProt ID

BAA95556

Shipping

Shipped on ice packs

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Anti-DNMT3L Antibody FL594 Conjugate (N117/9)

SKU: 75-153-FL594

Product Details

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