Transfected cell immunoblot: extracts of COS cells transiently transfected with untagged Kv2.1 and Flag-tagged DNMT3L, DNMT3A and DNMT3B plasmids and probed with N117/9 TC supe (left) and mouse anti-Flag (right).
Anti-DNMT3L Antibody
SKU: 75-153
Bulk Order Anti-DNMT3L Antibody
Product Details
DNMT3L
DNA (cytosine-5)-methyltransferase 3-like or DNMT3L is encoded by the gene DNMT3L. DNMT3l is a nuclear, catalytically inactive, regulatory factor of DNA methyltransferases. DNMT3L mediates transcriptional repression through interaction with histone deacetylase 1. It is thought to be required for the establishment of maternal genomic imprints. DNMT3L is expressed in several tissues including testis, ovary, and thymus. Diseases associated with DNMT3L include Testicular Spermatocytic Seminoma and Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome.
Purified
1 mg/mL
Monoclonal
N117/9
IgG1
ICC, WB
Mouse
DNMT3L
45 kDa
Fusion protein amino acids 1-387 (full-length) of human DNMT3L (also known as DNA (cytosine-5)-methyltransferase 3-like, accession number BAA95556); Rat: 66% identity (250/377 amino acids identical); Mouse: 65% identity (242/371 amino acids identical); ~40% identity with DNMT3A and DNMT3B
Human
AB_2094287
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.