Anti-Copper ATPase 1 (Menke's Disease Protein) Antibody (BSA and Azide free) (L60/4)

Name: Anti-Copper ATPase 1 (Menke's Disease Protein) Antibody (BSA and Azide free)
Brand: NeuroMab
SKU: 75-142-CF
Price: 486.0 USD
Availability: InStock

Our mouse Copper ATPase 1 (Menke's disease protein) carrier-free monoclonal antibody from NeuroMab is produced in-house from clone L60/4. It detects human, mouse, and rat Copper ATPase 1 (Menke's disease protein) and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Anti-Copper ATPase 1 (Menke's Disease Protein) Antibody (BSA and Azide free)

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Biotin

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Data Sheet

KO Validated

SKU: 75-142-CF

Volume: 100 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Copper ATPase 1 (Menke's disease protein)

Scientific Background

Copper-transporting ATPase 1 or ATPase Copper Transporting Alpha is encoded by the gene ATP7A and belongs to the cation transport ATPase (P-type) family. Copper-transporting ATPase 1 is a transmembrane enzyme that functions to provide copper to copper requiring proteins in the Golgi network and is also to remove excess copper across plasma membranes out of the cell. Copper-transporting ATPase 1 is found in most tissues except liver. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.6-1.0 mg/mL

Clonality

Monoclonal

Clone

L60/4

Isotype

IgG2b

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

ATP7A MC1 MNK

Molecular Weight

180 kDa in rat brain membrane preparations

Immunogen

Synthetic peptide amino acids 42-61 (cytoplasmic N- terminus) of human Copper-transporting ATPase 1 (accession number Q04656)

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Buffer

PBS

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Copper-transporting ATPase 1 (EC 3.6.3.54) (Copper pump 1) (Menkes disease-associated protein)

UniProt ID

Q04656

Shipping

Shipped on ice packs

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Anti-Copper ATPase 1 (Menke's Disease Protein) Antibody (BSA and Azide free) (L60/4)

SKU: 75-142-CF

Product Details

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