Anti-Conserved dopamine neurotrophic factor (CDNF) Antibody

Name: Anti-Conserved dopamine neurotrophic factor (CDNF) Antibody
Brand: Biosensis
SKU: R-1674-100
Price: 457.0 USD
Availability: InStock

Our Anti-Conserved dopamine neurotrophic factor (CDNF) rabbit polyclonal primary antibody detects human Conserved dopamine neurotrophic factor (CDNF), and is affinity-purified. It is validated for use in WB.

Western Blot testing of rabbit anti-CDNF antibody. Line 1. PageRuler Prestained Protein Ladder (#SM0671 Fermentas); Line 2. Recombinant CDNF expressed into the supernatant of CHO cell culture medium.

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Species Reactivity

Human

Applications

Host Species

Rabbit

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Data Sheet

SKU: R-1674-100

Volume/Size: 100 µg

Variant

Price:

$457.00

Quantity:

Product Details

Target

Conserved dopamine neurotrophic factor (CDNF)

Scientific Background

CDNF (conserved dopamine neurotrophic factor) is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- (Lindholm et al. 20007; Voutilainen et al., 2011) and MPTP-induced degeneration (Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson's disease. When administered after 6-OHDA or MPTP -lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.

Format

Affinity-purified

Clonality

Polyclonal

Isotype

IgG

Applications

Host Species

Rabbit

Immunogen

Recombinant human CDNF protein produced using CHO-based cell line. Purified from cell culture supernatant.

Immunogen Species

Human

Species Reactivity

Human

Storage

Store antibody stock solution at +4°C upon receipt. DO NOT FREEZE. This product is an (NH4)2SO4 precipitate. To use, mix well by pipetting or vortexing gently prior use, then withdraw the desired amount of antibody stock solution and dilute into your antibody dilution buffer and use normally.
Alternatively, material can be centrifuged at 10K x g for 5 minutes and the liquid sulfate solution carefully removed. Then precipitated antibody can be resuspended in 0.1M P, 250 mM NaCL, pH 7.4 solution. The solution should then be divided into working aliquots and stored at -80°C until used. Prevent multiple freeze thaw cycles of aliquots for best product life. Store at 2-8°C upon receipt; Do not freeze. See reconstitution instructions for handling information.

Physical State

Liquid

Buffer

Concentrated ammonium sulphate in PBS pH 7.4 containing no preservatives.

Dilution Ranges

WB: 1:6000-1:10000

Conjugate

Unconjugated

Specificity

CDNF (conserved dopamine neurotrophic factor).

Usage Statement

For research use only.

Country of Origin

United States

Expiration

12 months after date of receipt (unopened vial).

Synonyms

ARMETL1

UniProt ID

Q49AH0

Shipping

2-8°C (on cold packs)

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Anti-Conserved dopamine neurotrophic factor (CDNF) Antibody

SKU: R-1674-100

Product Details

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