Anti-Clcn4 Antibody (N222/6)

Name: Anti-Clcn4 Antibody
Brand: NeuroMab
SKU: 75-260
Price: 337.0 USD
Availability: InStock

Our mouse Clcn4 monoclonal antibody from NeuroMab is produced in-house from clone N222/6. It detects human, mouse, and rat Clcn4 and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Adult rat brain immunohistochemistry.

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-260

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Clcn4

Scientific Background

Chloride Voltage-Gated Channel 4, CLCN4 or H(+)/Cl(-) exchange transporter 4 is encoded by the gene CLCN4 and is a member of the voltage-gated chloride channel (ClC) family. CLCN4 is a proton-coupled chloride transporter. CLCN4 is expressed in skeletal muscle, brain and heart. Diseases associated with this gene include Raynaud-Claes Syndrome and X-Linked Intellectual Disability Syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N222/6

Isotype

IgG1

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

CLCN4

Molecular Weight

85 kDa

Immunogen

Synthetic peptide amino acids 43-64 (TDRHRKITSKSKESIWEFIKSL, cytoplasmic N-terminus) of human Clcn4 (accession number P51793)

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_10999754

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with Clcn5

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

H(+)/Cl(-) exchange transporter 4 (Chloride channel protein 4) (ClC-4) (Chloride transporter ClC-4)

UniProt ID

P51793

Shipping

Shipped on ice packs

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Anti-Clcn4 Antibody (N222/6)

SKU: 75-260

Product Details

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