Anti-Chapsyn-110/PSD-93 Antibody (N18/30)

Our mouse Chapsyn-110/PSD-93 monoclonal antibody from NeuroMab is produced in-house from clone N18/30. It detects human, mouse, rabbit, and rat Chapsyn-110/PSD-93 and is purified by Protein A chromatography. KO validated. Works in WB, IHC, ICC, IP, ELISA.

Immunolabeling of postnatal 14 mouse CA3 specifically labeling PSD93 (Cat. 75-057, 1:400, green) and Ankyrin G(red). DNA labeled with DAPI. Mice were transcardially perfused with ice-cold 4% paraformaldehyde in PBS, then brain removed and postfixed overnight. The 50uM slices were floating sections. Objective 25x, scale bar = 20um. Images kindly provided by Jorge Ramirez-Franco and Oussama El Far, Aix-Marseille Université and INSERM.
Immunoblot against crude membranes from whole adult rat brain (RBM) or hippocampi (MHM) from adult PSD-93/Chapsyn-110 knockout (KO) or wild-type (WT) mice. Mouse samples courtesy of Richard Huganir (Johns Hopkins University).
Immunofluorescence staining of cultured rat hippocampal neurons with N18/30 (red), K13/31 (Kv1.4, green) and rabbit anti- MAP2 (blue). Image courtesy of Yasuhiro Ogawa and Matthew Rasband (Baylor College of Medicine).
Adult rat brain hippocampus immunohistochemistry.
Cerebellum immunohistochemistry.
Immunoblot against crude membranes from whole adult mouse brain (MBM) or rat brain (RBM) and from human cerebral cortex [HBM(Cx)] or hippocampus [HBM(H)] probed with N18/30 (left) or N52A/42 (right) TC supe.
Surface representation of PSD93 labelling at the AIS of CA3 pyramidal neurons in WT (top panels) and Lgi1−/− (bottom panels) mouse hippocampi. Magenta: AnkG, Green: PSD93 (Cat. 75-057). Image from publication CC-BY-4.0. PMID:38663634
Immunolabeling of postnatal 14 mouse CA3 specifically labeling PSD93 (Cat. 75-057, 1:400, green) and Ankyrin G(red). DNA labeled with DAPI. Mice were transcardially perfused with ice-cold 4% paraformaldehyde in PBS, then brain removed and postfixed overnight. The 50uM slices were floating sections. Objective 25x, scale bar = 20um. Images kindly provided by Jorge Ramirez-Franco and Oussama El Far, Aix-Marseille Université and INSERM.
Immunolabeling of postnatal 14 mouse CA3 specifically labeling PSD93 (Cat. 75-057, 1:400, green) and Ankyrin G(red). DNA labeled with DAPI. Mice were transcardially perfused with ice-cold 4% paraformaldehyde in PBS, then brain removed and postfixed overnight. The 50uM slices were floating sections. Objective 25x, scale bar = 20um. Images kindly provided by Jorge Ramirez-Franco and Oussama El Far, Aix-Marseille Université and INSERM.
Click on image to zoom

Human, Mouse, Rabbit, Rat
ELISA, ICC, IHC, IP, WB
Mouse
490
550
594
650
Biotin
Carrier-Free

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Data Sheet
KO Validated KO Validated

SKU: 75-057

Volume: 100 µL
Price:
$337.00
Ships: 1-2 business days

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