Anti-c-FOS Recombinant Chicken Chimeric mAb FL650 Conjugate (N486/32)

Name: Anti-c-FOS Recombinant Chicken Chimeric mAb FL650 Conjugate
Brand: Aves Labs
SKU: 78-506-FL650
Price: 549.0 USD
Availability: InStock

Our Anti-c-FOS chicken recombinant primary antibody from Aves Labs is produced in-house from hybridoma clone N486/32. It detects human, mouse, and rat c-FOS, and is purified by affinity chromatography. It is great for use in IHC, ICC.

Anti-c-FOS Recombinant Chicken Chimeric mAb FL650 Conjugate

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Applications

ICC, IHC

Host Species

Chicken

Conjugates and Formulations

Unconjugated

490

550

594

Carrier-Free

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SKU: 78-506-FL650

Volume: 200 µL

Variant

Price:

$549.00

Quantity:

Ships: 1-5 business days

Product Details

Target

c-FOS

Scientific Background

C-fos belongs the Fos family. Other members include FosB, Fra-1, Fra-2. c-fos binds to JUN/AP1 transcription factor. C-Fos is expressed in placental tissue, fetal liver, developing bone, developing central nervous system, and adult bone marrow. It is expressed in the nucleus and in the endoplasmic reticulum. c-Fos has a role in signal transduction, cell proliferation, differentiation, and apoptosis. C-Fos is overexpressed in many cancers.

Format

Purified by affinity chromatography

Concentration

0.5 mg/mL

Clonality

Recombinant

Clone

N486/32

Isotype

IgY

Applications

ICC, IHC

Host Species

Chicken

Gene Name

FOS, G0S7

Molecular Weight

70 kDa

Excitation / Emission

FL650 Ex: 655 nm, Em: 676 nm

Immunogen

Fusion protein amino acids 1-377 (full-length) of human FOS (accession number P01100) produced recombinantly in E. Coli

Immunogen Species

Human

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

This recombinant antibody is a chimeric antibody created by replacing the mouse heavy and light constant regions of clone N486/32 with chicken IgY heavy and light constant regions. As such this antibody retains the same binding performance as the original clone N486/32 but can be detected using standard anti-chicken secondary antibodies allowing flexibility for multiplexing applications. This antibody is expressed recombinantly in mammalian cells and then affinity purified from the cell culture media and conjugated.

Buffer

1X PBS, 0.05% Sodium Azide pH 7.4

Conjugate

650

Specificity

No cross-reactivity reported

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7

UniProt ID

P01100

Shipping

Shipped on ice packs

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Anti-c-FOS Recombinant Chicken Chimeric mAb FL650 Conjugate (N486/32)

SKU: 78-506-FL650

Product Details

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