Anti-ADAM22 (Cytoplasmic) Antibody FL490 Conjugate (N46/30)

Name: Anti-ADAM22 (Cytoplasmic) Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-083-FL490
Price: 486.0 USD
Availability: InStock

Our mouse ADAM22 (cytoplasmic) FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N46/30. It detects human, mouse, and rat ADAM22 (cytoplasmic) and is purified by Protein A chromatography. KO validated. Works in IHC, ICC.

Anti-ADAM22 (Cytoplasmic) Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-083-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

ADAM22 (cytoplasmic)

Scientific Background

ADAM22 is a member of the ADAM (a disintegrin and metalloproteinase) family and predominantly expressed in brain. ADAM 22 is non-catalytic unlike other proteins in the family as it does not contain a zinc binding domain. ADAM22 is a post synaptic neuron receptor for LGI 1 and also binds LGI4. ADAM22 serve as an integrin ligand. Mutations in ADAM22 are implicated in early infantile epileptic encephalopathy-61 and Brachydactyly type C.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N46/30

Isotype

IgG2b

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Adam22

Molecular Weight

90 kDa

Immunogen

Fusion protein amino acids 757-857 (cytoplasmic region) of mouse ADAM22 (accession number Q9R1V6) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939316

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Disintegrin and metalloproteinase domain-containing protein 22 (ADAM 22)

UniProt ID

Q9R1V6

Shipping

Shipped on ice packs

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Anti-ADAM22 (Cytoplasmic) Antibody FL490 Conjugate (N46/30)

SKU: 75-083-FL490

Product Details

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