Anti-ADAM22 (Cytoplasmic) Antibody (N46/30)
Primary Antibody
Human, Mouse, Rat
N46/30
ICC, IHC, IP, WB
Mouse
Purified by Protein A chromatography
Adam22
90 kDa
![Immunoblot versus brain membranes from whole rat (RBM) and mouse (MBM) brain, and from human cerebral cortex [HBM(Cx)] and hippocampus [HBM(H)].](http://www.antibodiesinc.com/cdn/shop/products/validation-image-73-083-n46-30-wb-3_{width}x.jpg?v=1626905331)
Adult rat hippocampus immunohistochemistry.
![Immunoblot versus brain membranes from whole rat (RBM) and mouse (MBM) brain, and from human cerebral cortex [HBM(Cx)] and hippocampus [HBM(H)].](http://www.antibodiesinc.com/cdn/shop/products/validation-image-73-083-n46-30-wb-3_1024x.jpg?v=1626905331)
Product Specific References for Applications and Species
- Immunocytochemistry: Human | Rat
- Immunohistochemistry: Mouse | Rat
- Immunoprecipitation: Mouse
- Western Blot: Human | Mouse
| Immunocytochemistry: Human | ||
| PMID | Dilution | Publication |
| 37953841 | not listed | Nosková, L, et al. 2023. ADAM22 ethnic-specific variant reducing binding of membrane-associated guanylate kinases causes focal epilepsy and behavioural disorder. Brain Communications, . |
| Immunocytochemistry: Rat | ||
| PMID | Dilution | Publication |
| 31164806 | 1:100 | Bonetto, G., et al. 2019. Selective Axonal Expression of the Kv1 Channel Complex in Pre-myelinated GABAergic Hippocampal Neurons. Frontiers in cellular neuroscience, 222. |
| 30598502 | 1:100 | Hivert, B., et al. 2019. ADAM22 and ADAM23 modulate the targeting of the Kv1 channel-associated protein LGI1 to the axon initial segment. Journal of cell science, jcs219774. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 26269648 | not listed | Kole, M., et al. 2015. Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing. The Journal of neuroscience : the official journal of the Society for Neuroscience, 11433-11444. |
| Immunohistochemistry: Rat | ||
| PMID | Dilution | Publication |
| 20089912 | not listed | Ogawa, Y., et al. 2010. ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1038-1048. |
| Immunoprecipitation: Mouse | ||
| PMID | Dilution | Publication |
| 29670100 | 1:250 | Yamagata, A., et al. 2018. Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22. Nature communications, 1546. |
| Western Blot: Human | ||
| PMID | Dilution | Publication |
| 22473675 | not listed | Dhanchak, A., et al. 2012. Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis. Annals of neurology, 601-613. |
| 20463223 | not listed | Thomas, R., et al. 2010. LGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based growth inhibition. The Journal of neuroscience : the official journal of the Society for Neuroscience, 6607-6612. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 34910912 | not listed | Yokoi, N., et al. 2021. 14-3-3 proteins stabilize LGI1-ADAM22 levels to regulate seizure thresholds in mice. Cell reports, 110107. |
| 30846310 | 1:200 | Tai, Y., et al. 2019. Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM. Neuron, 358-372. |
| 28452394 | not listed | Frank, R., et al. 2017. Hierarchical organization and genetically separable subfamilies of PSD95 postsynaptic supercomplexes. Journal of neurochemistry, 504-511. |
| 26269648 | 1:200 | Kole, M., et al. 2015. Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing. The Journal of neuroscience : the official journal of the Society for Neuroscience, 11433-11444. |
| 25707359 | not listed | Chen, N., et al. 2015. Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes. Biochimica et biophysica acta, 827-833. |
| 19701204 | 1:1000 | Zhou, Y., et al. 2009. Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy. Nature medicine, 1208-1214. |