Anti-RAD17 Antibody

Name: Anti-RAD17 Antibody
Brand: PhosphoSolutions
SKU: 24132
Price: 456.0 USD
Availability: InStock

Our RAD17 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human RAD17 and is antigen affinity purified. It is great for use in WB.

Western Blot of human heart lysate showing specific immunolabeling of Rad17.

Click on image to zoom

Species Reactivity

Human

Applications

ELISA, WB

Host Species

Rabbit

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Data Sheet

SKU: 24132

Title: 100 µL

Variant

Price:

$456.00

Quantity:

Ships: 1-2 business days

Product Details

Target

RAD17

Scientific Background

Signals originating from damaged DNA activate checkpoint pathways and target the mitotic apparatus via a number a distinct mechanisms. These checkpoints link damage to DNA with the components of the cell cycle through signal transduction systems. The RAD17 gene product of Schizosaccharomyces pombe is an essential component of the checkpoint control pathway which responds to both DNA damage and disruption of replication.

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Host Species

Rabbit

Gene Name

RAD17

Immunogen

Synthetic peptide corresponding to amino acids from the N-terminal region of human RAD17 protein

Immunogen Species

Human

Species Reactivity

Human

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with the N-terminal region of human RAD17 protein

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Synonyms

CCYC; R24L; RAD17SP; RAD24; cell cycle checkpoint protein RAD17; RAD1 homolog; RAD17 homolog; RF-C activator 1 homolog; Rad17-like protein; cell cycle checkpoint protein (RAD17; Cell cycle checkpoint protein; RF C activator 1 homolog; HRAD 17

UniProt ID

O75943
UniProt Summary: Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the 9-1-1 (RAD1-RAD9-HUS1) complex and RHNO1 onto chromatin, and in CHEK1 activation. Involved in homologous recombination by mediating recruitment of the MRN complex to DNA damage sites. May also serve as a sensor of DNA replication progression.

NCBI Gene ID

5884

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Anti-RAD17 Antibody

SKU: 24132

Product Details

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