Monoclonal Antibodies

2872 products

Monoclonal antibodies are generated from hybridoma clones and are powerful research tools for analyzing proteins to understand biological and cellular functions.

We have a broad portfolio of monoclonal antibodies, including the NeuroMab line, which was developed in collaboration with the UC Davis – NIH facility. These highly-cited, highly-validated antibodies have been trusted by the neuroscience research community for years. Knockout validation guarantees target specificity and production from hybridoma clones provides batch-to-batch consistency and long-term supply.

Analysis of multiple proteins within the same tissue sample, using immunofluorescence is key to advancing research. To support the multiplexing field we provide fluorescent conjugates which include 490, 550, 594 and 650. Our mouse monoclonal conjugates continue to grow in popularity.

Showing 193 - 216 of 2872 products

Adult rat hippocampus immunohistochemistry.

Tissue and transfected cell immunoblot: extracts of rat brain membrane (RBM) and COS cells transiently transfected with V5-tagged AMIGO-1, AMIGO-2, AMIGO-3 or untagged Kv2.1 plasmid and probed with L86A/37 TC supe (left) plasmid and probed with L86A/37 TC supe (left).

NeuroMab Anti-AMIGO-1 Antibody

$329

Immunoblot of lysates from human skin fibroblasts from an ATP7A wild-type individual (ATP7A+/+, Lane 1) and three individuals with ATP7A null mutations (ATP7A-/-, Lanes 2-4) probed with L60/4 (top) and actin (bottom). Data courtesy of Stephanie Zlatic and Victor Faundez (Emory University). See reference 2017 Comstra et al., eLife (PMID 28355134) for further detail.

NeuroMab Anti-Copper ATPase 1 (Menke's Disease Protein) Antibody

$329

Confocal Z stack images taken from the 9–12 kHz cochlear region in noninjected control Myo7afl/fl (A), Myo7afl/fl Myo15-cre+/– (B), and Myo7afl/fl Myo15-cre+/– mice injected with AAV9-Myo7a (C) at P49–P54. AAV-Myo7a was injected between P13 and P15. Cochleae were labeled with antibodies against BK (Cat. 75-408, 1:200, magenta) and the IHC markers MYO7A (cyan) or MYO6 (gray). BK was almost complete absence in Myo7afl/fl Myo15-cre+/– mice (B). Image from publication, CC-BY-4.0. PMID: 39641274

Immunoblot against crude membranes from adult rat brain (RBM), wild-type (MBM-WT) and BKAlpha knockout (MBM- BKaKO) mouse brains probed with L6/23 (left), L6/60 (middle) or N52A/42 (right) TC supe. Reproduced from PLoS One (2010 Wersinger et al, PMID 21079807).

NeuroMab Anti-Slo1/BKAlpha Potassium Channel Antibody

$329

Adult rat optic nerve immunofluorescence staining L11A/41 (5 μg/ml)=red Rabbit anti-Caspr=green Image courtesy of Dr. Matthew Rasband.

NeuroMab Anti-Pan-Neurofascin Antibody

$329

Adult rat brain striatum and globus pallidus immunohistochemistry.

NeuroMab Anti-VGAT Antibody

$329

Immunoblot versus crude membranes from adult rat brain (RBM) and WT and KChIP3 KO mouse brains probed with K66/38 (left) and K55/82 (right) TC supe. Mouse samples courtesy of Takeshi Sakurai and Joseph Buxbaum (Mount Sinai School of Medicine).

NeuroMab Anti-KChIP3 K+ Channel Antibody

$329

Immunofluorescence staining transiently Kv1.6-transfected COS cells.

Immunoblot on adult rat brain membrane (RBM) and lysates from Kv1.6-transfected (COS+) and untransfected (COS-) COS cells.

NeuroMab Anti-Kv1.6 K+ Channel Antibody

$329

Adult rat brain immunohistochemistry (with antigen retrieval via sodium citrate pretreatment).

Immunoblot versus crude membranes from adult rat brain (RBM) and wild-type (WT) and LRRK2 KO mouse brains probed with 8G10 (left), N241A/34 (middle) and K89/34 (right) TC supe. Mouse brain samples provided by Xiaojie Li, Ted Dawson and Valina Dawson, Johns Hopkins University

NeuroMab Anti-LRRK2/Dardarin, N-Terminus Antibody

$385

NeuroMab Anti-ADAM11 Antibody (BSA and Azide free)

$475

Western blot analysis of A431 cells treated with calyculin A (100 nM) for 30 min (lane 1 and 2) then treated with lambda phosphatase (lane 3). The blot was probed with anti-Phosphoserine/threonine mouse monoclonal at 1:250 (lane 1) or 1:1000 (lanes 2 & 3).

Immunocytochemical labeling of phosphoserine and phosphothreonine in control and calyculin A-treated A431 cells. The cells were labeled with mouse monoclonal anti-Phosphoserine/threonine (PM3801) and rabbit polyclonal anti-Phosphoserine/threonine (PP2551), then the antibodies were detected using appropriate secondary antibodies conjugated to Cy3.

PhosphoSolutions Anti-Phosphoserine/threonine Antibody

$340

Western blot analysis of human umbilical vein endothelial cells untreated (lanes 1, 3, 5, & 7) or treated with pervanadate (1 mM) for 30 min. (lanes 2, 4, 6, & 8). The blot was probed with anti-EphA4 (N-terminal region) (lanes 1 & 2), anti-EphA4 (Tyr-779) (lanes 3 & 4), anti-EphA4 (Tyr-602) (lanes 5 & 6), or anti-EphA4 (C-terminal region) (lanes 7 & 8).

Western blot image of various mouse and human HCC cell lines expressing EphA4 (Cat. EM2801, 1:1000). Image from publication CC-BY-4.0. PMID: 38307859

PhosphoSolutions Anti-EphA4 (N-terminal region) Antibody

$340

Immunostaining of HeLa cells labeled with Anti-GAPDH (Cat. 600-GAPDH, 1:100, green) and nuclear staining with DAPI (blue). The anti-GAPDH produces strong cytoplasmic labeling of healthy cells.

Western blot of rat hippocampal lysate showing the specific immunolabeling of ~38 kDa GAPDH protein.

PhosphoSolutions Anti-Glyceraldehyde 3-Phosphate Dehydrogenase Antibody

From $160

Western blot of 10 µg of rat hippocampal lysate showing specific immunolabeling of the ~120 kDa NR1 subunit of the NMDA receptor.

PhosphoSolutions Anti-NMDA NR1 Subunit Antibody

$445

Western blot of neonatal rat brain lysate showing specific immunolabeling of the ~220-240 kDa nestin doublet.

Immunostaining of cultured E20 rat cortical neurons and glia stained with anti-nestin antibody (Cat. 1435-NES, red, 1:500) and anti-MAP2 antibody (Cat. 1100-MAP2, green, 1:500). The blue is Hoechst staining for nuclear DNA. The nestin antibody labels developing astrocytes and neuronal stem cells in a clearly filamentous fashion, while the MAP2 antibody stains dendrites and perikarya of mature neurons.

PhosphoSolutions Anti-Nestin Antibody

From $160

Western blot of mouse cortical lysate showing specific immunolabeling of the ~280 kDa MAP2 protein.

Immunostaining of rat hippocampus showing specific labeling of neuronal dendrites and perikarya with Anti-Microtubule Associated Protein 2 in green, FOX3 in red and nuclei in blue.

PhosphoSolutions Anti-Microtubule Associated Protein 2 (MAP2) Antibody

From $160

Immunofluorescence of a section of rat cerebellum selectively labeling the axons of granule cells with alpha-internexin (Cat. 100-AIN, 1:5000, green) and colabeled with anti-calretinin (red).

Immunofluorescence of cultured rat CNS cells showing specific labeling of neuronal processes with Anti-alpha-internexin (Cat. 100-AIN, 1:250, red), and specific labeling of perikarya and dendrites with anti-microtubule associated protein 2 (Cat. 1100-MAP2,1:2,500,green).

PhosphoSolutions Anti-Alpha Internexin/ NF-66 Antibody

From $150

NeuroMab Anti-Neuropeptide Y Antibody FL490 Conjugate

$474

NeuroMab Anti-Pan-Neurofascin (Extracellular) Antibody FL650 Conjugate

$531

NeuroMab Anti-Mortalin/GRP75 Antibody FL650 Conjugate

$474

Immunohistochemical staining of adult mouse retina showing specific immunolabeling of the ABCA4 protein (red, 1;100). Photo courtesy of Mary Raven, University of California, Santa Barbara, CA.

Western blot of 70 day old mouse retina lysate showing immunolabeling of the ~220 kDa ABCA4 protein at a dilution of 1:1000.

PhosphoSolutions Anti-ABCA4 (Rim Protein) Antibody

From $160

Immunostaining of CGRP (red) in cryopreserved DRG neurons grown on coverslips. 40xmag. Green staining is PGP9.5. Yellow staining is the colocalization of CGRP and PGP9.5. Cells were obtained and photo was provided courtesy of QBMCellScience.

PhosphoSolutions Anti-Calcitonin Gene Related Peptide (CGRP) Antibody

From $160

Immunofluorescence of HeLa cells labeled with anti-mitochondria antibody (1:100, green).

Western blot of HeLa cell lysate showing specific immunolabeling of the ~60 kDa mitochondrial protein.

PhosphoSolutions Anti-Mitochondria Antibody

From $150

NeuroMab Anti-GFP (Green Fluorescent Protein) Antibody

$329

$Immunoblot against membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] and probed with N81/37 (left) or N52A/42 (right) TC supe.$

NeuroMab Anti-GABA-B-R2 Antibody

$329

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Monoclonal Antibodies

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